The import of protein into chloroplasts is mediated by translocon components located in the chloroplast outer (the Toc proteins) and inner (the Tic proteins) envelope membranes. To identify intermediate steps during active import, we used sucrose density gradient centrifugation and blue-native polyacrylamide gel electrophoresis (BN-PAGE) to identify complexes of translocon components associated...

The import of protein into chloroplasts is mediated by translocon components located in the chloroplast outer (the Toc proteins) and inner (the Tic proteins) envelope membranes. To identify intermediate steps during active import, we used sucrose density gradient centrifugation and blue-native polyacrylamide gel electrophoresis (BN-PAGE) to identify complexes of translocon components associated...

When the theory of constraints (TOC) supply chain replenishment system (TOC-SCRS) is deployed in a plant or a central warehouse, replenishment frequency (RF) becomes one of the important decision parameters and depends on the sales or replenishment quantity (RQ) in the plant. The higher RF is preferred by TOC for the low inventory and the fast response to different market requirements. However,...

In its brief 20-year history, Goldratt's Theory of Constraints (TOC) methodology has evolved into a systems methodology that links elements of both soft and hard systems methods. The major component of TOC that underpins all the other parts of the methodology is the TOC Thinking Processes, a suite of logic trees that provide a roadmap for change. They guide the user through the decision making ...

Neuroendocrine tumor (NET) occurring in association with other endocrine syndromes forms a distinct entity. The aim was to assess the therapy response profile of the routine peptide receptor radionuclide therapy (PRRT) in this relatively uncommon but clinically challenging subgroup of patients. A retrospective analysis was undertaken from the case records from those who were treated with 177Lu-...

BACKGROUND Biologicals directed against tumour necrosis factor (TNF) have proven their efficacy in the treatment of spondyloarthritis and rheumatoid arthritis. We present a radiolabelling method for certolizumab pegol (CZP), a commercially available humanized Fab'-fragment directed against TNF. A biodistribution and dosimetry study was conducted. Tc-S-HYNIC CZP was synthesized. The in vitro TNF...

We studied discharges of organic carbon from eight contiguous small watersheds on the Atlantic Coastal Plain in Maryland for up to 24 yr. Six of these watersheds were second or third order with mixed-land-use, while two were first order (one completely forested and one highly dominated by cropland). These watersheds have perched aquifers, so all groundwater discharges as well as surface runoff ...

Introduction: The present study was aimed to assess the diagnostic performance of the two imaging methods of 131I-metaiodobenzylguanidine (131I-MIBG) and 99mTc-hydrazinonicotinyl-Tyr3-Octreotide (99mTc-HYNIC-TOC) in diagnosis and localization of pheochromocytoma and neuroblastoma. Methods: This study ...

With an aim to extract the structural information from the table of contents (TOC) to help develop digital document library the requirement of identifying/segmenting the TOC page is obvious. The objective to create digital document library is to provide a non-labour intensive, cheap and flexible way of storing, representing and managing the paper document in electronic form to facilitate indexi...

The preprotein translocon at the outer envelope membrane of chloroplasts (Toc) mediates the recognition and import of nuclear-encoded preproteins into chloroplasts. Two receptor components, Toc159 and Toc34, and the channel Toc75 form the Toc complex. In this study, we have analyzed the molecular architecture and organization of the Toc complex by blue native PAGE (BN-PAGE), which is a high-res...