RP-HPLC chromatographic method was developed for determination of Hyoscine Butyl Bromide (HBB) and Dipyrone ( DIP). In this method, HBB and DIP were separated by using C18 (25 cm×4.6 mm i.d. 5μm particle size) column as a stationary phase and using water: methanol (50:50) v/v pH adjusted to 7.0 with triflouroacetic acid and triethylamine) as a mobile phase, maintaining the flow rate at 1.0 mL m...

persea americana is a plant used by traditional medicine practitioners to treat ailments including diarrhoea and diabetes mellitus in nigeria. hence, the chloroform and the methanol fractions of the chloroform-methanol extract of the leaves of p. americana were evaluated for their acute toxicity as well as anti-diarrhoeal effects in wistar rats to substantiate this claim. the chloroform and met...

BACKGROUND Noisy breathing (death rattle) occurs in 23 to 92% of people who are dying. The cause of death rattle remains unproven but is presumed to be due to an accumulation of secretions in the airways. It is therefore managed physically (repositioning and clearing the upper airways of fluid with a mechanical sucker) or pharmacologically (with anticholinergic drugs). OBJECTIVES To describe ...