Orthopnoea is commonly attributed to heart failure but can be caused by diaphragm weakness, which, when severe, is often associated with hypercapnic respiratory failure. Bilateral diaphragm weakness is generally due to systemic nerve or muscle disease and usually occurs in the setting of severe generalized muscle weakness, but the diaphragm can be the initial or only muscle involved. Here, we r...

INTRODUCTION Acute hypercapnic respiratory failure (AHRF) is a serious condition observed in some patients with sleep apnea-hypopnea syndrome (SAHS). The objective of the present study was to study the clinical characteristics of SAHS patients who develop AHRF and their prognosis. PATIENTS AND METHOD A total of 70 consecutive SAHS patients who survived an AHRF episode and 70 SAHS patients pai...

BACKGROUND Nocturnal non-invasive ventilation (NIV) is an effective treatment for hypercapnic respiratory failure in patients with restrictive thoracic disease. We hypothesised that NIV may reverse respiratory failure by increasing the ventilatory response to carbon dioxide, reducing inspiratory muscle fatigue, or enhancing pulmonary mechanics. METHODS Twenty patients with restrictive disease...

Background: Acute respiratory failure (ARF) is one of the most common causes intensive care unit (ICU) admission and in-hospital mortality. In South Korea, about 25% patients admitted to ICU require mechanical ventilation. The mortality rate these 48%. Respiratory can be categorized based on pathophysiologic derangements, treatment options vary depending their classification. This study discuss...

Abstract Solitary fibrous tumors of the pleura (SFTPs) are rare primary pleural derived from sub-mesothelial mesenchymal tissue that mostly incidentally diagnosed in asymptomatic subjects. Symptomatic SFTPs usually present with dry cough and chest pain. We report case a 55-year-old lady 9-month history shortness breath, right-sided pain, heaviness, who presented to our institute hypercapnic res...