UNLABELLED INTRODUCTION In the treatment of secondary hyperparathyroidism of chronic kidney disease, calcimimetics - allosteric modulators of the calcium-sensing receptor - inhibit glandular hyperplasia and significantly reduce circulating parathyroid hormone levels. They have a major impact on the management of secondary hyperparathyroidism. CASE PRESENTATION We present the clinical case ...

We herein report a 39-year-old woman who had aggravated body pain, waddling gait, and fatigability for the past 2 years. A neurological examination showed hyperreflexia proximal muscle weakness. The serum calcium level was normal (10.1 mg/dL). However, alkaline phosphatase (3,855 IU/I) parathyroid hormone (1,008 pg/mL) levels were remarkably high. Cervical ultrasonography revealed goiter. patie...

Background/Aim: Pathological fractures are rare, suspicious and in some cases mentioned as the first sign of a malignant tumor. We present an uncommon case with pathological fracture tibia diaphysis severe hyperparathyroidism. Case Report: report female patient who was referred to emergency department history progressively worsening pain lower left leg inability fully bear weight. No trauma or ...

PURPOSE Despite recommendations for 99mTc-tetrofosmin dual tracer imaging for hyperparathyroidism in current guidelines, no report was published on dual-isotope 99mTc-tetrofosmin and 123I sodium iodide single-photon-emission-computed-tomography (SPECT). We evaluated diagnostic accuracy and the impact of preoperative SPECT on the surgical procedures and disease outcomes. METHODS Analysis of 70...

Based on the observation of a patient with a causal relationship between hyperparathyroidism and development of both autoimmune disease and paraproteinemia, we hypothesize a novel cause of autoimmunity triggered in the context of hyperparathyroidism.

Our experience in the field of surgery for renal hyperparathyroidism, gained from 640 cases, the largest number in the world, was reviewed. Additional comments were made on the relation between renal transplantation and renal hyperparathyroidism.

Primary hyperparathyroidism is increasingly being diagnosed subsequent to the detection of hypercalcaemia using multichannel auto-analyser screening. This paper provides a local picture of the clinical presentation and management of primary hyperparathyroidism. A retrospective review was conducted of 44 patients with primary hyperparathyroidism who were treated at the Queen Elizabeth Hospital b...

Hyperparathyroidism jaw tumour syndrome is a rare autosomal dominant inherited endocrine neoplasia syndrome, which predisposes carriers to develop a triad of multiple ossifying fibromas of the maxilla and mandible, parathyroid adenomas and carcinomas (with consequent hyperparathyroidism) as well as renal and uterine tumours. The prevalence of this condition is unknown. Patients typically presen...

The objective of our two case reports is to increase awareness of the simultaneous occurrence of primary hyperparathyroidism and malignancy in patients that presents with hypercalcaemia. This report reviews the case reports from the history, investigation, treatment and outcome for these two patients. A literature review of the association between malignancy and primary hyperparathyroidism was ...

A neonate was found to have normocalcaemic hyperparathyroidism with bone disease. The plasma parathyroid hormone concentration returned to normal by 4 weeks, and healing of the bone lesions was evident by age 5 months. The mother proved to have pseudohypoparathyroidism, previously unsuspected.