evaluation of enlarged follicles with unerupted teeth is always important because some changes may occur. one of the extremely rare conditions seen in dental follicles is multiple calcifying hyperplastic dental follicle. we report a case of multiple calcifying hyperplastic dental follicle. radiographs showed that mandibular third molars had a pericoronal radiolucent zone delineated by a well-de...

The ultrastructure of ethionine-induced hyperplastic liver nodules was compared to the adjacent nonnodular liver in the same rat and also to hyperplastic liver nodules induced by 2-fluorenylacetamide. Several reproducible cytostructural alterations were noted in ethionine-induced hyperplastic liver nodules of fasted animals but not in adjacent nonnodular liver. This set of alterations was quite...

BACKGROUND Friedreich ataxia (FA) causes distinctive lesions of dorsal root ganglia (DRG), including neuronal atrophy, satellite cell hyperplasia, and absorption of dying nerve cells into residual nodules. Two mechanisms may be involved: hypoplasia of DRG neurons from birth and superimposed iron (Fe)- and zinc (Zn)-mediated oxidative injury. This report presents a systematic analysis of DRG in ...

Background and aims: Colorectal adenomas are recognised as precursors of colorectal carcinomas. The significance of hyperplastic (metaplastic) colorectal polyps is unknown. The relationship between hyperplastic polyps and adenomas, and the prevalence and incidence of these lesions were evaluated in individuals predisposed to familial colorectal cancer. Methods: A total of 299 individuals partic...

BACKGROUND Hyperplastic polyps are common benign colorectal polyps, and are thought to have little association with malignant tumours in the colorectum. However, several reports suggest that some hyperplastic polyps may develop into colorectal neoplasms. AIM To clarify genetic alterations in colorectal hyperplastic polyps. METHODS Twenty eight colorectal polyps having serrated components we...

Inflammatory periapical lesions are characterized by infiltration of different immune cell types, the functions which depend on an effective vascular network. This study aimed to evaluate mast cells density (MCD) in inflamatory odontogenic cysts capsules concerning microvascular (MVD), area (MVA), and perimeter (MVP), correlate such findings with type lesion, intensity inflammatory infiltrate, ...

Peripheral giant cell granuloma (PGCG) is a non-neoplastic lesion representing a local hyperplastic reaction. It is a tumorlike pathologic condition arising on the buccal or lingual attached gingival or alveolar mucosa and the crest of the edentulous alveolar ridge, of uncertain etiology; it is probably a reactive lesion caused by chronic local irritants or trauma rather than a true neoplasm. P...

INTRODUCTION Cutaneous metaplastic synovial cyst (CMSC) is a rare cutaneous lesion characterized by a tender subcutaneous nodule, which usually occurs at the site of previous surgical or local trauma. Histologically, the lesion includes a cystic structure with villous-like projections and a lining mimicking hyperplastic synovium. CASE PRESENTATION We reported the first case of CMSC which deve...

BACKGROUND AND AIMS Colorectal adenomas are recognised as precursors of colorectal carcinomas. The significance of hyperplastic (metaplastic) colorectal polyps is unknown. The relationship between hyperplastic polyps and adenomas, and the prevalence and incidence of these lesions were evaluated in individuals predisposed to familial colorectal cancer. METHODS A total of 299 individuals partic...