PURPOSE To elucidate the role of partial splenic embolization (PSE) procedures, long-term outcome was assessed in terms of the recurrence of thrombocytopenia. METHODS A retrospective study was performed after 41 PSE procedures in 36 patients for hypersplenism owing to portal hypertension. The underlying disease was biliary atresia in 32 patients, extrahepatic portal obstruction in 3, and idio...

destruction, and the increased platelet level following splenectomy might be due to a decreased destruction of platelets. Likewise, the decreased level in hypersplenism might be due to an increased destruction. One approach to this problem is to label platelets in vitro, and then study their localization in the normal animal. The spleen contains a considerable amount of the label in such experi...

A growing body of evidence has supported the benefits of laparoscopic splenectomy (LS) for hypersplenism due to liver cirrhosis. With the increased proportion of elderly persons worldwide, it is necessary to investigate the risks and benefits of LS in elderly liver cirrhotic patients.From September 2003 to March 2012, LS and open splenectomy (OS) were performed for 21 (Group 1) and 19 (Group 3)...

Background: Neutropenia is reduction in the absolute number of neutrophils blood circulation. Common causes include increased destruction, reduced production, or excessive splenic sequestration. can be mild (Absolute Neutrophil Count (ANC) 1000-1500/L), moderate (ANC 500-1000/L), severe <500/L). Patients with neutropenia are presumed to at risk life-threatening infections. There lack informatio...

By Wau i H. CROSBY I HE WORDS hyposplenism and hypersplenism have enjoyed a long vogue. Hyposplenism, which may have been used first by Eppinger in 1913,1 has come to mean a pattern of changes that are due to or related to absence or atrophy of the spleen. Hypersplenism, coined by Chauffard in 1907,2 is more commonly used, but it describes a condition that is considerably less well defined. Hyp...

An adult girl, robust, without manifest cause, was attacked recently, towards the period of her menses, with a sudden severe hemorrhage from the nose, with bright but foul blood escaping together with a bloody vomiting of a very thick extremely black blood. Immediately there appeared about the neck and on the arms, spots partly black, partly violaceous or purple, such as are often seen in malig...

A 35 year old man with a fatal Campylobacter jejuni infection is described. He had HbE/beta zero thalassaemia and had undergone splenectomy nine months previously for hypersplenism; he also had chronic hepatitis C infection. He presented with high grade fever but no gastrointestinal symptoms and rapidly progressed to septicaemic shock and hepatic encephalopathy despite treatment with penicillin...

The etiology of idiopathic portal hypertension (IPH) is unknown. IPH is characterized by periportal fibrosis, portal hypertension, the formation of esophageal varices, and the development of portosystemic collateral vessels, splenomegaly, and secondary hypersplenism, all of which appear in the absence of hepatic cirrhosis (1). However, there are clinical situations that can coexist with IPH tha...

A family with congenital hepatic fibrosis (CHF) and congenital heart disease (CHD) is presented. The consanguineous healthy parents gave birth to 12 children of whom 10 survived. One son had CHF and CHD, one daughter had CHF and a second daughter had CHD. Three other siblings probably had small a ventricular septal defect and another one probably had mild pulmonary valve stenosis. Development o...