An uncommon coexistence of circumscribed hyperpigmentation and hypopigmentation, in close proximity to each other, is described in a 17 years old patient with various other cogenital defects, such as dysmorphic facial appearance, severe kyphoscoliosis, delayed motor development, epileptic seizures, and mental retardation. We suggest the combination of hyper- and hypopigmented cutaneous lesions ...

BACKGROUND AND OBJECTIVE Cutaneous brown discolorations in the area of injection can be a cosmetically bothersome side effect from a parenteral iron treatment, and have not responded to an effective therapy until now. STUDY DESIGN/PATIENTS AND METHODS We report retrospectively on five patients who were treated with the Q-switched ruby and/or Nd:YAG laser for circumscripted siderosis after int...

Piebaldism is a rare autosomal-dominant disorder of melanocyte development characterized by congenital poliosis and stable patches of leukoderma. Initially, these clinical features may be the presenting signs of various syndromes or associated diseases, which should be considered in the differential diagnosis. We present the case of a 14-year-old adolescent girl with piebaldism, along with a re...

Vitiligo is an acquired leukoderma that results from the loss of epidermal melanocytes, and is characterized by macules and patches of depigmented skin. With a relatively high rate of prevalence, vitiligo occurs in localized, generalized, or segmental patterns; it can run a rapidly progressive course or remain stationary. The pathogenesis of vitiligo is not yet fully understood, but the autoimm...

By Assistant Surgeon A. "Wood, M.D. Reading somewhere, a short time ago, an article on the diagnosis between white leprosy and leucoderma, which then greatly interested me, I was soon afterwards gratified by having to treat a case of the latter, so well marked, as perhaps to justify my offering a few remarks thereon, in the hope that they may prove as acceptable to others, as the actual observa...

In addition to hypopigmentation of the skin and red iris colouration, albino animals also display distinct physiological and behavioural alterations. However, information on the social interactions of albino animals is rare and has mostly been limited to specially bred strains of albino rodents and animals from unique environments in caves. Differentiating between the effects of albinism and do...

Fractional resurfacing may be used in the management of melasma, striae/stretch marks, acne scars, pearly penile papule, syringoma, burn scar, verrucous epidermal naevus and skin tightening. In 20-30% of the patients with melasma, fractional resurfacing may not be effective or may even cause an exacerbation. Treatment effects may also be temporary. When compared with traditional carbon dioxide ...