The administration of thiouracil induced a rise and administration of thyroid substance a decrease of the plasma cholesterol concentration in rats. The concentration and daily output of bile cholesterol was markedly reduced in hypothyroid rats and markedly increased in hyperthyroid rats. Evidence is presented which suggests that the rate of synthesis of cholesterol is significantly increased in...

Aim of this study was to see any effect on respiratory functions in hypothyroid patients after pranayama (yoga). The subjects for the study were 20 hypothyroid females, 39.70 +/- 8.27 years of mean age referred from medicine department of UCMS & G.T.B. Hospital. Spiro metric recordings were taken with hypair (version-1.28). Baseline (first) recordings were taken when patient came for the first ...

Thyroid-related hormones regulate the efficiency and expression of sarco-endoplasmic reticulum calcium ATPases in cardiac and skeletal muscle. However, little is known about the relationship between thyroid hormones and calcium (Ca2+) homeostasis in the brain. It is hypothesized that manipulating rat thyroid hormone levels would induce significant brain Ca2+ adaptations consistent with clinical...

Patients with long-standing hypothyroid are, in some cases, reported to develop pituitary gland hyperplasia due to loss of feedback inhibition of thyroxine in hypothalamus-the condition of which typically regresses after thyroxine replacement. Herein, a 15-year-old girl-with long-standing untreated lingual hypothyroid-presents with a pathologically proven TSH pituitary macroadenoma and bilatera...

The administration of thiouracil induced a rise and administration of thyroid substance a decrease of the plasma cholesterol concentration in rats. The concentration and daily output of bile cholesterol was markedly reduced in hypothyroid rats and markedly increased in hyperthyroid rats. Evidence is presented which suggests that the rate of synthesis of cholesterol is significantly increased in...

Neonatal hypothyroidism markedly retarded the postnatal development of three ketone-body-metabolizing enzymes in rat brain during the first 4 weeks after birth. In contrast with normal animals, the brains of hypothyroid rats did not show decreases in the activities of these enzymes during the immediate postweaning period. The activities of ketone-body-oxidizing enzymes were markedly diminished ...

Normal level of thyroid hormones is important for normal hepatic function and thyroid dysfunction may modulate metabolic function of liver. The purpose of this study is to determine whether liver function is associated with subclinical and overt hypothyroidism. Thyroid and liver function tests were evaluated in 47 patients with overt (TSH ≥10.0 mIU/L) and 77 patients with subclinical hypothyroi...

In the present study serum concentrations of T3, T4, TSH were measured in 140 goitrous school children, aged 6-12 yrs of both sexes from Siddhartnagar, located in sub-Himalayan tarai region of Eastern Uttar Pradesh where endemic goiter and iodine deficiency are prevalent. The results show that overall 10.0% studied population (12.9% boys and 7.7% girls) has TSH level above 6.1μIU/ml indicating ...

Cardiovascular disease is one of the major complications of hypothyroidism which is one of the most common endocrine disorders in India. In the present study, we have analyzed the link among oxidative stress, C reactive protein which is an inflammatory marker and the cardiovascular lipid risk factors in hypothyroid patients which has not been analyzed before. Sixty seven untreated hypothyroid p...