نتایج جستجو برای: icam1 gene
تعداد نتایج: 1141596 فیلتر نتایج به سال:
INTRODUCTION Myocardial infarction is caused by the obstruction of an artery in places of atherosclerosis plaque rupture. Endothelial cells during their activation express chemoattractant and adhesion molecules whereas infiltrating inflammatory cells produce enzymes, predisposing a lesion to rupture. MATERIAL AND METHODS We investigated the correlation between polymorphisms in the human genes...
Amniotic membrane proved to be very effective tool in the treatment of a number of ocular surface diseases. The amniotic membrane, however, has to be stored before its transplantation onto the ocular surface followed by mandatory serologic control in order to exclude the transmission of certain viruses. Therefore it is most important to study if cryopreservation of the membrane affects cell sur...
Meta-analyses of European populations has successfully identified genetic variants in over 100 loci associated with lipid levels, but our knowledge in other ethnicities remains limited. To address this, we performed dense genotyping of ∼2,000 candidate genes in 7,657 African Americans, 1,315 Hispanics and 841 East Asians, using the IBC array, a custom ∼50,000 SNP genotyping array. Meta-analyses...
Increased endothelial cell (EC) permeability and vascular inflammation along with alveolar epithelial damage are key features of acute lung injury (ALI). Products of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine oxidation (OxPAPC) showed protective effects against inflammatory signaling and vascular EC barrier dysfunction induced by gram-negative bacterial wall lipopolysaccharide (L...
Theoretical predictions of several measurable quantities, which are relevant in K-, Dand Bmeson phenomenology, depend on the matrix elements of some ∆F = 2 four-fermion operators. Examples are given by FCNC effects in SUSY extensions of the Standard Model [1]-[2], by the B s– B̄ s width difference [3] and by the O(1/m 3 b) corrections in inclusive b-hadron decay rates (which actually depend on t...
We investigate O’Raifeartaigh-type models for F-term supersymmetry breaking in gauge mediation scenarios in the presence of gravity. It is pointed out that the vacuum structure of those models is such that in metastable vacua gravity mediation contribution to scalar masses is always suppressed to the level below 1 percent, almost sufficient for avoiding FCNC problem. Close to that limit, gravit...
The electroweak structures of the FCNC-induced rare and radiative K decays are presented. While the former decays are sensitive to short-distance physics and offer exceptional probes for new physics, the latter are dominated by long-distance physics. Even so, they should not be set aside since they constitute essential ingredients to control the hadronic uncertainties occurring for the rare dec...
In this work, we update the constraints on tree level FCNC couplings in the framework of a theory with n isosinglet vector-like down quarks. In this context, we emphasize the sensitivity of the B → J/ψKS CP asymmetry to the presence of new vector-like down quarks. This CP asymmetry, together with the rare decays B → Xs,dll̄ and K → πνν̄ are the best options to further constrain the FCNC tree leve...
Patients with low-grade myelodysplastic syndromes (MDS) show high levels of tumor necrosis factor α (TNFα) and up-regulation of apoptosis in the marrow. In contrast, marrow cells in advanced MDS are typically resistant to TNFα-induced apoptosis but are rendered apoptosis-sensitive on coculture with stroma. The present studies show that CD34(+) marrow cells in advanced MDS express high levels of...
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