1. Kantarjian H, Ravandi F, O’Brien S, et al. Intensive chemotherapy does not benefit most older patients (age 70 years or older) with acute myeloid leukemia. Blood. 2010;116(22):4422-4429. 2. Juliusson G, Antunovic P, Derolf A, et al. Age and acute myeloid leukemia: real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry. Blood. 2009;113(18):4179-4187. 3. Jul...

The primary goal of acute myeloid leukemia chemotherapy is to obtain a complete remission. In adults with de novo disease, response rates reach between sixty and seventy per cent with classical '3 + 7' or DAT schemes. Curative postinduction treatments are now available for responsive patients, which makes it mandatory to look for more effective modalities of induction therapy. Experience gather...

A 40-year-old female at 26-week gestation was diagnosed with acute promyelocytic leukemia (APL) after an abnormal prenatal lab workup showed pancytopenia. She was treated with all-trans-retinoic acid (ATRA), idarubicin, and dexamethasone. After day one of treatment, she developed differentiation syndrome, which was treated with dexamethasone. At 30-week gestation, she had preterm premature rupt...

A highly sensitive electrochemical DNA sensor for detection of the chemotherapeutic drug idarubicin mediated by Methylene blue (MB) has been developed. from fish sperm immobilized at electropolymerized layers Azure B. The incorporation MB into substantially increased sensitivity. concentration range determination cyclic voltammetry was 1 fM to 0.1 nM, with a limit (LOD) 0.3 fM. Electrochemical ...

STATEMENT OF THE PROBLEM Many members in the IDA are not actively involved in the association. Therefore, despite representation being a key function of the IDA, members are not equally represented in the association. PURPOSE OF THE STUDY This study aimed to examine IDA members' views, with a view to identifying changes that might enhance the members' active engagement. MATERIALS AND METHOD...

Necessary and sufficient conditions are given to guarantee associativity of algebras and co-algebras. As main application, it is discussed the associativity of the tensor algebra T (V ) of a free module V over any commutative ring R. 1. Review of basic definitions Recall that a vector space A, or more generally a (free) module over a commutative ring R is an R-algebra if a multiplication map mA...

This paper studies the role of US political factors in the allocation of World Bank concessional lending, where US political interests are proxied by voting similarity in the United Nations General Assembly on issues identified as important by the US Department of State. In contrast to previous studies we find that the US exerted a significant influence on IDA lending during the period 1993 200...