The seroprevalence of toxoplasmosis in 832 pregnant women in Miracema, Rio de Janeiro, was determined and 75.1% (625) and 2.0% (17) were anti-Toxoplasma gondii IgG and IgM positive, respectively. Out of the 17 IgM positive pregnant women, only one had low avidity IgG corresponding to the acute phase of the infection. All the other women presented with high avidity IgG and also presented with re...

An immunoenzymatic method for the detection of IgM antibodies (IgM-ELISA) against a fraction of Schistosoma mansoni adult worm antigen, soluble in trichloroacetic acid (TCA-soluble fraction), was evaluated for epidemiological purposes in low endemic areas for schistosomiasis. Blood samples on filter paper were collected from a population living in the municipality of Pedro de Toledo, São Paulo ...

Background: IgG antibodies specific for the SARS-CoV-2 Spike protein are under intensive investigation urgent need to identify a correlate of protective immunity in individuals vaccinated with licensed and candidate COVID-19 vaccines. Limited data available on vaccine-elicited IgM their potential implication SARS-CoV-2. Methods: We performed longitudinal study quantify spike (IgG-S IgM-S) 1873 ...

We experienced an 85-year-old male patient with selective IgM deficiency. The average levels of his serum immunoglobulins were as follows: IgG, 1,165 mg/dl, IgA 280 mg/dl, and IgM 17 mg/dl. The subpopulations of peripheral blood lymphocytes in this patient were normal, including normal numbers of IgM-bearing lymphocytes. Normal amounts of cells with cytoplasmic IgM were induced by in vitro addi...