By ROBERT SCHREK, FREDERICK W. PRESTON AND ALBERT A. DIErz A PRELIMINARY REPORT’ showed that rabbit anti-dog lymphocyte serum was more toxic in vitro to leukemic than to normal human lymphocytes. This paper presents detailed data on the toxicity of this immune heterobogous serum. As the dog lymphocytes have the Forssman antigen and rabbits are Forssman negative,2 it was necessary to consider wh...

introduction: immune system is involved in the etiology and pathophysiology of inflammation and vitamins are important sources of substances inducing nonspecific immunomodulatory effects. given the proinflammatory role of cytokines in the inflammation and pain induction, this study aimed to assess the effects of long-term administration of vitamin b1 on the proinflammatory cytokines, edema, and...

While the phagocytosis of Renibacterium salmoninarum by rainbow trout macrophages in vitro occurred in the absence of serum factors, opsonized bacteria once phagocytosed survived for a longer period than bacteria not exposed to serum. Immune sera favoured survival to a greater extent than non-immune sera. Although heat-inactivated immune sera reduced the extent of bacterial killing, bacterial p...

The ability of virulent strains of Aeromonas salmonicida to resist the bactericidal activity of serum was quantitated. The A. salmonicida strains tested included virulent strains, mutants lacking the major surface A-protein, and mutants lacking A-protein and having a modified lipopolysaccharide structure. The sera evaluated included normal human, rabbit, and trout sera, immune trout serum, and ...

The effect of replacing dietary Zn supplemented from inorganic (ZnCO3) source with organic Zn (Zn methionine; Zn-met) was investigated in 72 rats (98.42 ± 1.483 g) by randomly allotting to 4 diets (6 replicates/diet, 3 rats/replicate). Basal diet was prepared with purified ingredients without Zn. The control diet (AIN-76A) contained 12 ppm of Zn from ZnCO3 (100-I). In the other diets ZnCO3 was ...

More than 70 years have passed since the prophylactic treatment of rabies with dried attenuated vaccine was first reported by L. Pasteur1. But the treatment of rabies to-day still remaines on the same therapeutic principles of giving active immunity by repeated injections of an emulsion prepared of the nervetissue of animals infected with fixed virus before the street virus invades into and pro...

Immunological tolerance produced in rabbits by neonatal injections of BSA can be terminated by a series of injections of certain heterologous serum albumins which cross-react with BSA. Injections of albumins distantly related to BSA were more effective in terminating the tolerant state than injections of albumins closely related to BSA. It was concluded from results obtained with several hetero...

Objective(s):In this study, the serum level of interferon-γ (IFN- γ) and interlukin-4 (IL-4) was evaluated as a marker of Th1 and Th2 immune response that influence the clinical course of cutaneous leishmaniasis[r1] . Materials and Methods: This cross-sectional study was conducted on 44 cases of cutaneous leishmaniasis (21 cases with healed lesions and 23 cases with chronic non-healing lesions...

In the mouse model of Lyme borreliosis, the host immune response during infection with Borrelia burgdorferi results in the remission of carditis and arthritis, as well as global reduction of spirochete numbers in tissues, without elimination of infection. These events were recapitulated by passive transfer of immune serum from infected immunocompetent mice or T-cell-deficient mice to severe com...

In the present study,we examined the effects of exposure to radiofrequency(RF)with intermediate frequency (IF) range at 40 kHz on immune response using a stress-induced immune suppression method and on concentrations of serum corticosterone in mice. We used antibody-forming cell (AFC) assay to evaluate the effects of RF radiation at 40 kHz on immune response in mice. The number of plaques forme...