To perform IgG avidity immunoblotting assay for detection of acute toxoplasmosis, 100 serum samples were collected from Tehran, Iran. The presence of Toxoplasma-specific IgG and IgM antibodies were checked by commercial Trinity kit. Samples were categorized in acute and chronic phases of Toxoplasma gondii infection according to IgG avidity ELISA. IgG avidity immunoblotting was performed, and an...

AIMS To determine whether IgG immunoblotting can improve the diagnosis of ocular toxoplasmosis. METHODS Samples of serum were tested from patients with ocular lesions that could be caused by toxoplasmosis. All such samples from Scotland and Northern Ireland are usually referred to the Scottish Toxoplasma Reference Laboratory. From questionnaires filled out by the clinicians, two groups of ser...

Alkylhydroperoxide reductase (AhpC, the 26 kDa antigen) is one of the abundant antioxidant enzymes in Helicobacter pylori and seems to have a good potential for use in development of immunoassays to detect H. pylori infection in clinical specimens. This study aimed to investigate some properties of this antigen by the produced monoclonal antibodies. Five established hybridoma cell lines secreti...

Retinoids can be used to treat and prevent the formation of basal cell carcinoma (BCC) squamous carcinomas (SCCs; notably cutaneous oral SCC). Preferentially Expressed Antigen in Melanoma (PRAME), a gamete-specific repressor retinoid-induced differentiation, is ectopically expressed BCC SCC tumors. However, effects PRAME on development these cancers their sensitivity retinoid therapies are unkn...