Zygomycosis is an opportunistic fungal infection with a high mortality rate. It is known to cause invasive disease in immunocompromised hosts but it may produce only cutaneous/ subcutaneous infections in immunocompetent hosts. Treatment is difficult due to its fulminant course and lack of effective anti-fungal drugs. Here, we report a rare case of subcutaneous zygomycosis caused by Mucor hiemal...

The blood-brain barrier prevents infiltration of peripheral immunocompetent cells into the CNS under physiological conditions. Following brain trauma there is reported a rapid and massive immunological response. Our earlier data indicated that surgical brain injury causes breaking of brain parenchyma integrity and results in cell changes and death, astrogliosis and disruption of blood vessels. ...

BACKGROUND To report the clinical course of PML in an apparently immunocompetent patient treated with cidofovir. CASE PRESENTATION A 35-year-old immunocompetent man who developed progressive hemianopsia, aphasia, and limb weakness underwent repeated MRI scans of the brain, spinal fluid analyses, and brain biopsy. Before diagnosis was established based on brain biopsy, he was consecutively tre...

Disseminated necrotizing leukoencephalopathy (DNL) is characterized by multiple microscopic foci of white matter necrosis. DNL was initially thought to be exclusively associated with immunosuppression conditions but it has been recently described in immunocompetent patients in septic shock. A 90-year-old immunocompetent woman with no previous neurological impairment presented with septic shock ...

INTRODUCTION Isolated cryptococcal pneumonia in the immunocompetent host is a rare infection. Indications for treatment and its duration are currently not defined. CLINICAL PICTURE Three patients presented with cavitating cryptococcal pneumonia. TREATMENT They were treated with oral fluconazole. OUTCOME Improvement was evident clinically, radiologically and serologically. Fluconazole was ...

Objective: Demodex folliculorum and brevis are two species known to settle on the skin of humans. mite infections called demodicosis. Demodicosis, which is usually asymptomatic, cause some diseases as a result an imbalance in immune system mechanisms This study was conducted investigate relationship between spp. infestations clinical signs, such immunodeficiency, rosacea, blepharitis facial itc...

The present study examined the effects of Vitacel raw fiber on great sturgeon (Huso huso) immunocompetent cell population size including lymphocyte and neutrophil populations and lysozyme activity after oral administration of the feed and Vitacel at 1.3% of the feed for 90 days. Generally, a significant increase was seen in the neutrophil count of fish receiving Vitacel as compared to the contr...

A total of 450 stool samples were collected from inpatient and outpatient clinics of Pediatric Department, Minia University Hospital, Minia District, Egypt. Two groups of patients were studied, including 200 immunosuppressed and 250 immunocompetent children. Stool samples were subjected to wet saline and iodine mounts. A concentration technique (formol-ether sedimentation method) was carried ou...

Cryptococcal meningoencephalitis is a leading of morbidity and mortality in immunocompromised individuals worldwide. However, there are few documented cases in immunocompetent patients. We present a rare case of disseminated Cryptococcus with progression to meningoencephalitis in an immunocompetent patient, with a possible atypical presentation. Magnetic resonance imaging of the brain and elect...

Varicella zoster virus (VZV) is a human neurotropic alphaherpesvirus that causes chickenpox (varicella) in children. VZV reactivation may lead to neurological complications, including transverse myelitis. However, transverse myelitis caused by VZV reactivation is rare in immunocompetent patients. Herein, we report a case of transverse myelitis caused by VZV in an immunocompetent older patient, ...