BACKGROUND Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, associated with immunosuppression states. As there are only some non-published documents concerning PML in HIV infected patients in Portugal, we pretend to characterize natural history of PML infection in a population of HIV patients. METHODS We retrospectively reviewed, from ...

INTRODUCCION: Hasta ahora existen pocos estudios sobre las caracteristicas clinicas de la poblacion pediatrica con neumonia por COVID-19. El objetivo este estudio fue analizar los datos que se asocian el desarrollo en ninos y adolescentes infeccion SARS-CoV-2 Mexico. METODOS: Se llevo a cabo un analisis secundario base Direccion General Epidemiologia del Gobierno Mexicano. incluyeron menores 19...

Abstract This retrospective cohort study examined our practice for the management of basal cell carcinoma (BCC) in very elderly, to identify subgroups where intervention could be minimized, based on frailty and trends survival. All patients aged ≥ 90 years with histologically confirmed BCC during 2017 2018 were included within (n = 319). Data lesion characteristics (size, location subtype), pre...

Background The increasing number of patients experiencing periprosthetic total knee arthroplasty (TKA) infections and the cost of treating them suggest that we seek alternatives to two-stage revision. Single-stage revision is a potential alternative to the standard two-stage procedure because it involves only one surgical procedure, so if it is comparably effective, it would be associated with ...

We report an intracerebral abscess caused by a recently identified nocardial species, in an immunocompetent individual without extraneural involvement. A 63-year-old non-smoking Caucasian male with an unremarkable history of hypertension, presented with a 2-week history of personality changes including apathy, some difficulty walking, a tendency to veer to the left and a possible seizure. Preli...

A 21-year-old man presented to the eye casualty department via optician referral. He complained of loss of vision in his right eye 5 days previously. The optician queried a macular bleed and unilateral ‘papilloedema’ of the right eye. The patient gave a history of general malaise for a number of months with anorexia, headaches and weight loss over a period of weeks. It was noted that he had dev...

BACKGROUND The spread of West Nile virus across North America and evidence of transmission by transfusion prompted the U.S. Food and Drug Administration to encourage the development of methods to screen the blood supply. OBJECTIVE To assess the cost-effectiveness of nucleic acid amplification testing for West Nile virus in the U.S. blood supply. DESIGN Markov cohort simulation. DATA SOURC...

IMPORTANCE Patients with basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (SCC) (often termed nonmelanoma skin cancer or keratinocyte carcinoma [KC]) often develop new KCs, but information is limited on the frequency and timing of these subsequent tumors. This information is crucial to guide follow-up care. OBJECTIVE To determine the timing of subsequent new KCs in patients wh...

BACKGROUND The increasing number of patients experiencing periprosthetic total knee arthroplasty (TKA) infections and the cost of treating them suggest that we seek alternatives to two-stage revision. Single-stage revision is a potential alternative to the standard two-stage procedure because it involves only one surgical procedure, so if it is comparably effective, it would be associated with ...

BACKGROUND Symptomatic vulvovaginal candidiasis (VVC) is one of the most common problems leading women to seek advice in primary healthcare facilities. AIM The aim of this study is to describe the associations between some hypothesized factors and the presence of symptomatic VVC. SUBJECTS AND METHODS An analytical cross-sectional study was conducted. A total of 90 women diagnosed with sympt...