in spite of very high sensitivity, bone scan is quite nonspecific in evaluation of bony lesions. in interpretation of bone scan special attention to patient’s clinical presentation and correlation with other lab and imaging modalities should be paid. in this report a patient with erdheim chester disease a rare and unusual form of lipidosis is presented and the pattern of 99mtc-mdp bone scan and...

Technetium-99m methoxyisobutylisonitrile (99mTc-MIBI) uptake is known to be increased in breast cancer because of increased blood flow from angiogenesis and heightened metabolism. We performed a 99mTc-MIBI scan in a patient with mammary Paget's disease. The patient had underlying invasive cancer in the same side of the breast. 99mTc-MIBI scan exhibited a scintigraphic image of the uptake from t...

a 57-year-old male with history of prostatectomy, cyctectomy, cecal urinary diversion for invasive prostate cancer and with a recent rise in psa level, was referred for bone scintigraphy to rule out osseous metastatic disease. an interesting finding was abnormal tracer accumulation throughout the large bowel, which was proved to be due to urinary diversion.

Pixon noise reduction was applied to 18 planar images, six each from 99mTc-methylene diphosphonate (99mTc-MDP), 67Ga citrate (67Ga), and (123)I-metaiodobenzylguanidine ((123)I-MIBG) studies. Pixon processing increased patient signal-to-noise ratio, 6.8-11.8 fold. Three specialists preferred processed images 44 of 54 times with good agreement (87%). Most (9/10, p<0.02) of the null and negative p...

FROM JAPAN The Effect of Cisplatin on Kidney Uptake of Technetium-99m-MDP in Rats Tachio Sato, Seiro Yoshioka, Yoshinao Abe, Jutaro Takahashi, Kenji Yamada, Hiroshi Fukuda, Yuko Ogata and Masao Tada Departments of Nuclear Medicine, Radiology and Molecular Neurology, Institute of Development, Aging and Cancer, Tohoku University and the Department of Radiology, Sendai Kosei Hospital, Sendai, Japa...

Two deoxyglucose (DG) derivatives, (α,β)-2-deoxy-2-amino(ethylcarbamate)-D-glucose (ECB-DG) and (α,β)-2-deoxy-2-amino(1,2-dihydroxypropyl)-D-glucose (DHP-DG), were synthesized and radiolabeled successfully with [99mTc(H2O)3(CO)3]+ complex. [99mTc]-ECB-DG and [99mTc]-DHP-DG complexes were prepared (96% and 93% radiochemical purities respectively) by using 46 mCi of Na99mTcO4 in 1 mL saline. Radi...

Stanford University, Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, USA Here we prospectively compared the combined 18F NaF/18F FDG PET/ MRI against 99mTc-MDP in patients with breast and prostate cancers. Twelve patients referred for 99mTc-MDP bone scans were prospectively enrolled from Oct 14 Jan 15. The cohort included 6 men with prostate cancer and 6 women with ...

Bone scan was performed a 77 years old man with prostatic carcinoma. The planar 3h 99mTc-methylenediphosphonate (MDP) whole-body bone scan did not reveal skeletal metastases. However, on the anterior view, unexpected, large, round shaped activity in the liver projection was noted (Panel A). Further investigation disclosed that the patient had been operated for hepatic hemangioma thirty years ag...

UNLABELLED Antibodies accumulate nonspecifically in infectious foci due to the locally increased vascular permeability. This study describes a method of infection imaging in which 99mTc-DTPA (diethylenetriaminepentaacetic acid) is trapped at the target by a previously administered anti-DTPA monoclonal antibody. DTIn1. METHODS Rats with Staphylococcus aureus-infected calf muscle were injected ...

Purpose: To assess the role of 18F-NaF PET/CT in detection metastatic bone disease compared to 99mTc-MDP scan (+/-SPECT/CT). Methods: 64 adult patients with locally advanced primary tumor were enrolled this study. All underwent pretherapy and scan. Results: Among revealed positive metastases 26 patients, only 19 them have results scan, while remaining 7 falsely negative On other hand diagnosed ...