results two bacterial types, st208, and st218, were identified in all 140 samples. the st208 mainly came from icu and department of respiratory medicine, while st218 from department of plastic surgery; 70.21% of st208 and 84.78% of st218 were carbapenem-resistant acinetobacter baumannii (crab) and carbapenem-susceptible acinetobacter baumannii (csab), respectively. multidrug-resistance genes in...

background and objectives: patients at intensive-care-unit (icu) are at risk of acquiring nosocomial infections which contributes to higher rates. approximately 25% of all hospital infections and 90% of outbreaks occur in icus. multi-resistant gram-negative rods are important pathogens in icus, causing high rate of mortality. the purpose of this study was to investigate the antimicrobial resist...

conclusions the present study showed that bla oxa-23-like was the most frequent carbapenemase identified among carbapenem-resistant a. baumannii isolated in tehran hospitals. evaluation of antibiotic resistance genes in a. baumannii, is necessary to control further dissemination of these antibiotic resistant genes. results results showed that 123 of 131 (93.89%) acinetobacter species, possessed...

The increase of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) poses a worldwide and serious health threat. Although new antibiotics, such as daptomycin and linezolid, have been developed for the treatment of infections of Gram-positive pathogens, the emergence of daptomycin-resistant and linezolid-resistant strains during therapy has now increase...

In order to understand the role of the mar locus in Salmonella with regard to multiple antibiotic resistance, cyclohexane resistance, and outer membrane protein F (OmpF) regulation, a marA::gfp reporter mutant was constructed in an antibiotic-sensitive Salmonella enterica serovar Typhimurium DT104 background. Salicylate induced marA, whereas a number of antibiotics, disinfectants, and various g...

background & objective: urinary tract infection (uti) is a common disease in adults that early diagnosis and proper treatment of it has high importance. this study was performed for analysis of type and antibiotics resistance of isolated bacteria from urine of adult in different sex and ages for help in choose of antibiotics in empirical therapy.method: data of patients (gender, age, kind o...

conclusions the simultaneous detection of e. faecalis in a patient’s gastrointestinal and urine tracts can indicate the presence of uropathogenic enterococcus. further study is essential to identify virulence factors involved in the colonization of these isolates in the urinary tract. background urinary tract infection (uti) is one of the most common bacterial infections in outpatient settings....

conclusions although different source of p. aeruginosa may involve in patient colonization, genetically related strains were isolated from different wards and or the same ward of the hospital. our results pointed to the restriction of currently used antibiotics in studied hospital. we hope that our results cast light on the control and transmission of the infection in the investigated hospital....

BACKGROUND Antibiotic homogeneity is thought to drive resistance but in vivo data are lacking. In this study, we determined the impact of antibiotic homogeneity per se, and of cefepime versus antipseudomonal penicillin/β-lactamase inhibitor combinations (APP-β), on the likelihood of infection or colonisation with antibiotic resistant bacteria and/or two commonly resistant nosocomial pathogens (...

There has been a dramatic increase in the emergence of antibiotic-resistant bacterial strains, which has made antibiotic choices for infection control increasingly limited and more expensive. In the U.S. alone, antibiotic-resistant bacteria cause at least 2 million infections and 23,000 deaths a year resulting in a $55-70 billion per year economic impact. Antibiotics are critical to the success...