As an uncommon, malignant salivary gland tumor with female predominance, hyalinizing clear cell carcinoma (HCCC) is regarded as an indolent tumor. The diagnosis of this rare tumor is challenging, and it depends on microscopic and immunohistochemical (IHC) studies. Although it is regarded as an indolent tumor, there are reports of unconventional forms with aggressive clinical courses. We report ...

Bendamustine is an alkylating agent which also shows properties of a purine analog. Because of its unique mechanism of action it shows activity in relapsed indolent lymphomas which are resistant to alkylating agents, purine analogs, and rituximab. Bendamustine has a favorable toxicity profile causing no alopecia and only a moderate hematotoxicity and gastrointestinal toxicity. Combinations of b...

We discuss the formation of spectral features in the decelerating ejecta of gamma-ray bursts, including the possible effect of inhomogeneities. These should lead to blueshifted and broadened absorption edges and resonant features, especially from H and He. An external neutral ISM could produce detectable H and He, as well as Fe X-ray absorption edges and lines. Hypernova scenarios may be diagno...

Ende Mai 2012 stellte sich der zu diesem Zeitpunkt 63-jährige Patient wegen zweier Schwellungen am linken Oberschenkel hausärztlich vor. Diese zeigten indolent, derb aber gut verschieblich. Gemäss Patientenwunsch erfolgte die Zuweisung zur nächstgelegenen chirurgischen Klinik operativen Entfernung.

The myelodysplastic syndromes (MDS) provide a clinical model for evaluating the evolution of a relatively indolent malignancy into one which is frankly aggressive. The morbidity and mortality in this myeloid clonal hemopathy relate to either marrow dysfunction associated with ineffective hematopoiesis and its peripheral blood cytopenias or to disease evolution into a variant of acute myeloid le...

Systemic mastocytosis is characterized by bone marrow involvement, which requires a bone marrow biopsy for diagnostic work-up. We questioned whether bone marrow involvement could be predicted using biochemical markers. We selected patients with various symptoms suggestive of indolent systemic mastocytosis, of whom 63 ultimately had bone marrow involvement. Patients suspected of aggressive masto...

Introduction Carcinomas of the salivary glands represent a rare tumor group. The following is case hepatic metastatic carcinoma duct. patient presented due to indolent swelling left parotid gland with extension ipsilateral cervical lymph nodes and facial nerve paresis.