Telomerase is the enzyme that maintains telomere length by adding telomeric repeats after each cell division. Numerous metabolic factors such as obesity, insulin resistance or physical inactivity have been associated with shortened telomeres. In the present study, we assessed telomerase activity in diabetic patients having or not foot ulcer. A total of 90 adult patients with type 2 diabetes mel...

Diabetic foot ulcer (DFU) is a severe complication of diabetes mellitus (DM). Patients with DFU have increased mortality and morbidity as well decreased quality life (QoL). The present scoping review aims to study the social issues diabetic foot. Following PRISMA guidelines, was conducted in two databases (Scopus Pubmed) use following keywords: “social aspects foot”, characteristics “demographi...

Diabetic foot ulcer (DFU) is the major global and devastating complication of diabetes mellitus that affects at least 20% of diabetic patients during their lifetime. This article presents an overview of the research evidence on maggot debridement therapy that serves as a guide to health professionals who may be users of this form of treatment now and in the future. It is a time to apply this sa...

background: epidemiological characteristics of diabetic foot infection in our region are not clear. the purpose of this study was to determine the epidemiological features of diabetic foot infection in babol, north of iran. methods: from march, 2005 to april, 2010, the epidemiological features of 450 cases of diabetic foot infection treated in two main teaching hospitals of babol medical univer...

BACKGROUND Diabetic foot ulceration is receiving more attention because of its high amputation and mortality rate. It is essential to establish the frequency of amputations in people with diabetes after any change to the management of diabetic foot care. The present study aim to compare the frequency of lower-extremity amputations in patients with diabetes foot ulcer over a ten-year period. M...

BACKGROUND Although Diabetes mellitus is a major public health problem in the Middle East and North Africa (MENA) region with high rates of diabetic foot complications, there are only limited data concerning mortality among such a high risk group. Therefore, the main aim of the current study was to assess all-cause mortality and its related predictors among diabetic patients with and without di...

OBJECTIVE The purpose of this study was to determine whether a strategy of aggressive cardiovascular risk management reduced the mortality associated with diabetic foot ulceration. RESEARCH DESIGN AND METHODS After an initial audit of outcomes demonstrating a high mortality rate in 404 diabetic foot ulcer patients with the first ulceration developing between 1995 and 1999, a new aggressive ca...

Background Diabetic foot complications are acknowledged as the leading cause of amputation and diabetes-related hospitalisation. Podiatry-led multi-disciplinary clinics are recognised as important strategies to improve diabetic foot outcomes. Data suggests diabetic foot complications are increasing at a faster rate than diabetes is being diagnosed. A reliable, competent workforce is urgently re...

Diabetes mellitus is one of the most common metabolic diseases. More than 154 million people are estimated to have diabetes worldwide. The prevalence of diabetes among veterans has increased to 17%, more than double the prevalence in the general population. Diabetic foot ulcers are a frequent late complication in diabetic patients and the most prevalent lesion of the diabetic foot. Foot examina...

D iabetic foot ulcers burden the U.S. health care system with an annual cost of approximately $6 billion (1). Based on the mechanical etiology of diabetic foot lesions, investigators tried to establish a relationship between ulcer occurrence and plantar pressures. Mostly, peak pressure has been chosen as an ulcer predictor. However, previous studies have yielded only moderate correlations betwe...