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CONTEXT Group A beta-hemolytic streptococcus (GABHS) pharyngitis is a common childhood illness. The clinical diagnosis is difficult to determine and laboratory tests have limitations; hence, the condition is generally overdiagnosed and overtreated. Several clinical pediatric-specific predictive models have been published but none have been prospectively studied. OBJECTIVE To test the performa...

OBJECTIVE To assess the association between features of acute sore throat and the growth of streptococci from culturing a throat swab. DESIGN Diagnostic cohort. SETTING UK general practices. PARTICIPANTS Patients aged 5 or over presenting with an acute sore throat. Patients were recruited for a second cohort (cohort 2, n=517) consecutively after the first (cohort 1, n=606) from similar pr...

in this study, immunohistochemistry was used to clarify the early stages of viral kinetics and cycliccourse of ibdv, ir499, which has been described earlier as a very virulent strain (vvibdv). fifteen, 4-week-old spf chickens were inoculated with 10³ eid50 of vvibdv, ir499, via oculo/nasal route. five birdsserved as controls, and inoculated with phosphate buffered saline (pbs). the birds were t...

The matrix protein 2 (M2) blocker, Amantadin, is approved by FDA to treat and control of influenza A virus infections in children and adults. Recently, some substitutions at amino acid positions are causing the emergence of anti viral drug-resistant strains of influenza virus. To investigate the frequency of Amantadin resistance among influenza A viruses isolated in children (up to 10 years old...

A total of 27 different isolates of Haemophilus paragallinarum were made from chickens between June 1991 and December 1992. All of these isolates were examined by ELISA, by means of a locally produced panel of three monoclonal antibodies (denoted F1, V1 and VF3). The isolates were all of the F1 antigenic type. Three of them showed a weak reaction with the F1 monoclonal antibody, while three oth...

To determine the magnitude of the problem posed by primary dengue infection in children and the distinctive clinical clues that may differ from those with secondary infection, 996 children serologically diagnosed with dengue infection and admitted to the Department of Pediatrics, Chulalongkorn Hospital, Bangkok, Thailand between 1988 and 1995 were retrospectively reviewed. One hundred and thirt...

infectious keratoconjunctivitis (ikc) is a painful, highly contagious ocular disease in sheep and goats. this study was carried out for identification and characterization of causative agent of ocular disease in a sheep flock consisting of 300 ewes in mashhad, iran. several ocular swabs were taken from affected animals. the samples were pooled and processed in a laboratory for isolation of susp...