background: inflammation is a dynamic process that is elicited in response to various harmful stimulantsthat may threaten the well-being of the host. herbs have been traditionally used as anti-inflammatory agents since very early times. rubia tinctorum l. is one of these herbs that havebeen used for treating inflammatory diseases in iranian traditional medicine. objective: this study aims at co...

introduction: it appears that some risk factors for coronary heart diseases (chd) initiate their influence in the childhood period and their clinical complications start to take effect in adulthood. it is possible that adolescent active or sedentary boys, have other inflammatory silent risk factors of chd, in addition to routine risk factors such as lipid profile. however, the scientific data a...

objectives: iron chelators, such as maltol and kojic acid, have antioxidant and anti-inflammatory properties. they may have beneficial effects on inflammatory bowel disease (ibd) because iron can develop and aggravate inflammation in ibd. in the present study, the effect of selected iron chelators and anti-oxidants were evaluated on a model of trinitrobenzene sulfonic acid (tnbs)-induced coliti...

ascites in the course of crohn's diseases is rare and is usually a sign of a concomitant malignancy, infection or thrombosis of portal or hepatic vein. herein, we reported on a 26-year-old man who was initially admitted with severe crohn's ileocolitis complicated by copious exudative ascites, abdominal pain and sever diarrhea. in our patient, we could not find any of the aforementioned conditio...

purpose: to report a case of delayed corneal perforation secondary to topical diclofenac usage after myopic lasek and review of literature. patients and findings: a 25-year-old female with history of myopic lasek 2 months before referred to her surgeon with epithelial defect, stromal thinning and infiltration. she was treated with antimicrobial medications for infectious keratitis for one week....

background sepsis is one of the most important causes of morbidity and mortality in the intensive care units (icus). it is difficult to accurately differentiate sepsis from similar diseases rapidly. therefore, it becomes critical to identify any biomarker with the ability of differentiation between sepsis and nonsepsis conditions. the urokinase plasminogen activator receptor has been implicated...

the main inflammatory bowel disorders are including celiac disease (cd), inflammatory bowel diseases (ibd) and irritable bowel syndrome (ibs). celiac disease is a digestive and autoimmune disorder that can damage the small intestine and characterized by a multitude gastrointestinal (gi) and extra gi symptoms. ibd (including ulcerative colitis and crohn’s disease) is a group of inflammatory cond...

purpose: risk factors of pelvic inflammatory disease can be different in different countries because of different sexual behaviors and religious restrictions. this study investigated the risk factors of this disease in iranian women in tehran. materials and methods: in this cross-sectional, descriptive study 1104 women with pelvic inflammatory disease were assessed from may 2010 to march 2011. ...

procalcitonin (pct) is a precursor peptide for the hormone calcitonin and is frequently increased in overt sepsis. the aim of this study was to test diagnostic accuracy of procalcitonin among patients with positive systemic inflammatory response syndrome (sirs) in identifying sepsis. in this cross sectional study, from 563 patients with positive sirs admitted through the emergency department of...

the aim of the present study was to investigate the potential of nanoemulsion formulation for topical delivery of clobetasol propionate (cp) using algal oil (containing omega-3 fatty acids) as the oil phase. cp has anti-inflammatory, immunomodulatory and antiproliferative activities. however, its clinical use is restricted to some extent due to its poor permeability across the skin. algal oil w...