based on the extensive application of peganum harmala (p.h) seeds in the asian traditional medicine, we tried to investigate its possible anxiety effect. method: the effect of p.h. extract inhalation was evaluated in adult male rats using elevated plus-maze apparatus. the humidity of prepared ethanol extract was 37%. animals in different groups (n=6) received 2, 4, 6, 12 or 18 gr/ml doses of th...

backgrounds: all of long-acting β2-agonists are beneficial in maintenance treatment of asthma but their use in relieving acute asthma attacks is not well known. the aim of this study was to compare rapid bronchodilatory effects of salmeterol and formoterol in patient with moderate to severe asthma. methods: it was a randomized, double blind, cross-over study on 60 patients with moderate to seve...

introduction: spontaneous perforation of the nasal septum is an uncommon condition. nasal inhalation of substances such as cocaine has long been linked to this perforation. case report: this report describes the case of a 46-year-old woman who was addicted to methamphetamine and who presented with perforation of the nasal septum.this is the first reported case of nasal septal necrosis linked to...

PURPOSE Adherence to inhalation therapy is a critical determinant of the success of chronic obstructive pulmonary disease (COPD) management. However, in practice, nonadherence to inhalation therapy is very common in COPD patients. The effects of adherence to inhalation therapy in COPD have not been fully studied, and less is known about the relationship between medication adherence and quality ...

BACKGROUND Inhalation injury has high mortality and carries a significant risk of permanent pulmonary dysfunction. Inhalation injury and its consequences impose difficulties for the respiratory therapists, nurses and doctors who play a central role in its clinical management. In this study, we aimed to report our clinical experience and the role of non-invasive mechanic ventilatory (NIMV) suppo...

Inhalation of cold air in guinea pigs increases total pulmonary resistance (RL), an effect that is mediated by kinins and tachykinins. Bronchoconstriction induced by bradykinin (BK) inhalation in guinea pigs is markedly inhibited by nitric oxide (NO) release from the airway epithelium. We investigated whether endogenous NO modulates the increase in RL induced by inhalation of cold air. In anest...

BACKGROUND Inhalation of thermal water with antioxidant properties is empirically used for COPD. AIMS To evaluate the effects of sulphurous thermal water (reducing agents) on airway oxidant stress and clinical outcomes in COPD. METHODS Forty moderate-to-severe COPD patients were randomly assigned to receive 12-day inhalation with sulphurous thermal water or isotonic saline. Patients were as...

The deposition efficiency of unsteady inhalation is investigated in present study by using computational fluid dynamics techniques. Comparison with steady inhalation is also discussed. The inspiratory cycle of a realistic unsteady inhalation profile was applied at the outlet of nasopharynx, which has the maximum flow rate of 40.3L/min. Aerodynamic particle sizes of 5μm and 20μm were studied in ...

Thirty two fire victims with smoke inhalation, with or without burns, and 26 control subjects had bronchoalveolar lavage performed. Cell yields and differential cell counts were assessed. All patients and controls were cigarette smokers. Patients with smoke inhalation (SI) injury generally showed higher total bronchoalveolar lavage (BAL) cell yields, and this was significant on repeat lavage fr...

Fluorocarbons are widely used in industry, and manifestations of inhalation toxicity include polymer fume fever, reactive airways dysfunction, and bronchospasm. Only seven cases of alveolitis occurring acutely after inhalation have been reported. This paper presents four cases of toxic pneumonitis due to direct inhalation of industrial fluorocarbon used as a waterproofing spray for horse rugs. ...