Increasing evidence indicates that inflammation plays an important role in the pathogenesis of hepatic ischemia-reperfusion (I/R) injury. However, it is still unclear how I/R stimuli induce inflammatory responses in the liver. NLRP3 is an intracellular pattern recognition receptor and a component of NLRP3 inflammasomes that can induce caspase-1 activation, and regulate the processing of a poten...

BACKGROUND Previous injury is often proposed to be a risk factor for football injury, but most studies rely on players reporting their own medical history and are thus potentially subject to recall bias. Little is known about the natural variation in injury pattern between seasons. OBJECTIVES To study whether prospectively recorded injuries during one season are associated with injuries susta...

BACKGROUND Reliable epidemiological information on injury burden and pattern is essential to formulate effective injury control and prevention strategies. Injury surveillance systems are globally gaining ground as a tool for collecting such systematic data on injuries, but less so in low and middle income countries. This study describes the experience of setting up a District Level Hospital-Bas...

Background: Motorcyclists are among the most vulnerable groups of road accident victims, who are prone to a growingmortality rate due to the constant rise in the number of accidents. This study was performed to investigate the injurypatterns among motorcyclist trauma patients admitted to Kamyab Hospital, the largest trauma center affiliated withMashhad Univercity of Medical Sc...

BACKGROUND The aim of this study was to evaluate the demographics, mechanisms, pattern, injury severity, and the outcome (ie, length of intensive care unit [ICU] stay, length of mechanical ventilation, total length of stay, mortality) in multiple-injured children based on a review from the German trauma registry study ("Traumaregister") of the German Society of Trauma Surgery (Deutsche Gesellsc...

BACKGROUND Basketball is the second most popular sport in Nigeria after football and is commonly played by adolescents. Prospective studies on adolescent basketball players in Nigeria are lacking. Such studies will help to develop injury counter-measures. Hence, this study aimed at determining the incidence and pattern of injuries among adolescent basketball players in Nigeria. METHODS A pros...

Neurological involvement is not uncommon in patients who sustain electrical injury. The exact mechanism of nervous system damage following electrical trauma is not fully understood. The gamut of possible neurologic manifestations following electrical injury is diverse. This case report describes a young man with a unique pattern of neurological injury following an electrical burn. The combinati...

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