High Intensity Focused ultrasound (HIFU) is a non-invasive cancer therapy that makes use of the mainly thermal effects of ultrasound to destroy tissue. In order to achieve reliable treatment planning, it is necessary to characterise the ultrasound source (transducer) and to understand how the wave propagates in tissue and the energy deposition in the focal region. This novel exploratory study i...

High Intensity Focused Ultrasound (HIFU) has been emerging as a new and effective modality in non-invasive thermal ablation for cancers and solid tumours. Although a theoretical model is available for calculating thermal field and the consequent lesion production, its computation is too time-consuming (~ 1 day) for HIFU treatment planning on the site. In this study, several approximations were ...

Methods Multiparametric MRI combined with both systematic and fusion biopsy is being utilized more frequently worldwide to select patients for focal therapy. The ability to effectively ablate prostate cancer with transrectal HIFU has been demonstrated by numerous publications to date. Early results from focal HIFU series suggest that side effect profiles such as stricture, erectile dysfunction,...

non-invasive ultrasound surgeries such as high intensity focused ultrasound have been developed to treat tumors or to stop bleeding. in this technique, incorporation of a suitable imaging modality to monitor and control the treatments is essential so several imaging methods such as x-ray, magnetic resonance imaging and ultrasound imaging have been proposed to monitor the induced thermal lesions...

High intensity focused ultrasound (HIFU) has been used noninvasively for therapeutic applications. Previous studies have shown that HIFU when targeted on fetal rat and mice bones resulted in hemorrhage. Hemorrhage occurrence and area were found to correlate with total equivalent energy (i.e. product of energy density, number of pulses and volume of the focal region) and surface power (i.e. prod...

Avascular areas on contrast-enhanced magnetic resonance imaging have been considered to be areas of localized prostate cancer successfully treated by high-intensity focused ultrasound. However, the optimal timing of magnetic resonance imaging has not been discussed. The thermal effect of high-intensity focused ultrasound is degraded by regional prostatic blood flow. Conversely, the mechanical e...

High-intensity focused ultrasound (HIFU) is a minimally invasive technique that has been used for the treatment of both benign and malignant tumours. With HIFU, an ultrasound (US) beam propagates through soft tissue as a high-frequency pressure wave. The US beam is focused at a small target volume, and due to the energy building up at this site, the temperature rises, causing coagulative necros...

BACKGROUND Non-invasive high-intensity focused ultrasound (HIFU) can be used to treat a variety of disorders, including those in the brain. However, the differences in acoustic properties between the skull and the surrounding soft tissue cause aberrations in the path of the ultrasonic beam, hindering or preventing treatment. METHODS We present a method for correcting these aberrations that is...