Background and Aims: Chronic hepatitis C is one of the most important etiologies of cirrhosis and hepatocellular carcinoma worldwide. Clinical condition of hepatic patients and the outcome of chemotherapy are under impact of Hepatitis C virus (HCV) genotypes. Therefore, HCV genotyping is important for prediction of success of chemotherapy and progression of liver diseases. Methods: In thi...

hemophiliac patients carry a high risk for blood born viruses particularly hepatitis c virus (hcv) infection. with introducing the new therapeutic modalities for hiv infection, the role of hcv in mortality and morbidity has been more prominent. hiv co-infection is a wellknown factor that accelerates the progression of liver injury leading to end stage liver failure. screening of hemophiliacs ha...

background: viral infections such as epstein-barr virus and herpes simplex virus may play a role in the pathogenesis of behçet’s disease (bd). interferons (inf) are natural defense mechanisms against viruses and inhibit their activities by enhancing major histocompatibility complex class i and cytokine expression. this study evaluated the efficacy of inf-α-2b on mucocutaneous lesions of bd.   m...

INTRODUCTION Hepatitis C virus reinfection occurs universally after liver transplantation with accelerated cirrhosis rates of up to 30% within 5 years after liver transplantation. Management of hepatitis C virus reinfection is complicated by drug interactions and pre-treatment. Dual antiviral therapy with pegylated interferon and ribavirin only reaches sustained virological response rates of ap...

Two cases of obstinate cancers are cured by a new hypothesis synergistic therapy approach where Cancer Homoeotherapeutics were analysed scientifically immunotherapy modus operandi homoeopathic medicine selection is done activating natural cancer immunity killer cells (NK) through the interferon produced viral infection. So synthesis antiviral and antimiasmatic to treat cases.

BACKGROUND/AIMS Interferon-based treatment is not appropriate for a large number of patients with chronic hepatitis C for various medical and social reasons. Newly developed directly acting antivirals (DAAs) have been used to treat chronic hepatitis C without severe adverse effects and have achieved a sustained viral response (SVR) rate of 80-90% with short treatment duration. We were intereste...

chronic granulomatous disease is an inherited defect in intracellular killing of ingested microorganisms characterized by recurrent life threatening bacterial and fungal infections including invasive aspergillosis in early childhood. we report  a  disseminated aspergillosis as  the  representative  of  adult  onset  chronic granulomatous disease without previous infection, with dramatic respons...

background: interferons (ifns) are common therapeutics for several diseases such as viral hepatitis, multiple sclerosis and malignancy. a variety of autoimmune related side effects have been observed during ifn therapy. rare cases of myopathy, polymyositis or dermatomyositis have been reported during therapy with high doses of ifn^5. case presentation: in this report, we describe a case with se...