Background: Interleukin-17 (IL-17) is a proinflammatory cytokine that involved in the pathogenesis of several autoimmune and inflammatory diseases. Inflammation testis male-reproductive tracts may lead to male infertility.Objective: To assess seminal plasma IL-17 infertile patients evaluate its relation different parameters.Patients Methods: Fifty with primary infertility were included addition...

We investigated the potential role of IL-17A in the induction of granulocyte colony-stimulating factor (G-CSF), a critical granulopoietic growth factor, in human renal proximal tubular epithelial cells. Human renal proximal tubular cells (HK-2, ATCC) were used to characterize the effects of IL-17A or IL-17F on G-CSF production, using ELISA, real-time RT-PCR, and immunoblotting. The cell surface...