نتایج جستجو برای: interleukin 23
تعداد نتایج: 280903 فیلتر نتایج به سال:
IL-23p19 deficient mice have revealed a critical role of IL-23 in the development of experimental autoimmune diseases, such as collagen-induced arthritis (CIA). Neutralizing IL-23 after onset of CIA in rats has been shown to reduce paw volume, but the effect on synovial inflammation and the immunological autoimmune response is not clear. In this study, we examined the role of IL-23 at different...
Exfoliative cheilitis is an inflammatory condition that can significantly impair quality of life. This the first reported case interleukin-23 inhibitor, tildrakizumab, for treatment a chronic, refractory exfoliative cheilitis.
A protective function for interleukin 23 (IL‐23)‐IL‐17 axis in abdominal aortic aneurysm development
BACKGROUND The human leukocyte antigen (HLA)-B27 gene is considered to be a major gene associated with predisposition to ankylosing spondylitis (AS); however, studies have demonstrated that non-HLA-B27 genes also contribute substantially to the susceptibility to AS. Two single nucleotide polymorphisms (SNPs), rs1004819 and rs10889677, of the interleukin-23 receptor (IL-23R) gene have been shown...
The T helper type 1 (Th1) immune response plays an important role in protective immunity, pathophysiology and development of tuberculosis (TB). To investigate whether osteopontin (OPN) and other Th1 response-related molecules are associated withTB disease status, including co-infection with HIV, and response to anti-TB treatment, circulating levels of full-length OPN (F-OPN), thrombin-cleaved N...
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