Baeyer-Villiger monooxygenases catalyze the oxidation of carbonylic substrates to ester or lactone products using NADPH as electron donor and molecular oxygen as oxidative reactant. Using protein engineering, kinetics, microspectrophotometry, crystallography, and intermediate analogs, we have captured several snapshots along the catalytic cycle which highlight key features in enzyme catalysis. ...

We study the elasticity of fibrous materials composed of generalized stiff polymers. It is shown that, in contrast to cellular foam-like structures, affine strain fields are generically unstable. Instead, a subtle interplay between the architecture of the network and the elastic properties of its building blocks leads to intriguing mechanical properties with intermediate asymptotic scaling regi...

In this paper, a Meir-Keeler contraction is introduced to propose a viscosity-projection approximation method for finding a common element of the set of solutions of a family of general equilibrium problems and the set of fixed points of asymptotically strict pseudocontractions in the intermediate sense. Strong convergence of the viscosity iterative sequences is obtained under some suitable con...

Hierarchical models of visual processing assume that global pattern recognition is contingent on the progressive integration of local elements across larger spatial regions, operating from early through intermediate to higher-level cortical regions. Here, we present results from neuropsychological fMRI that refute such models. We report two patients, one with lesions to intermediate ventral reg...

A model is developed to study the in vivo intermediate filament organization in terms of repartition between four different structural states: soluble proteins, particles, short, and long filaments. An analysis is conducted, showing that the system has a unique, globally asymptotically stable equilibrium. By means of sensitivity analysis, the influence of parameters on the system is studied. It...

Test method facet is one of the factors which can have an influence on the test takers’ performance. The purpose of the current study was to investigate the effects of two different response types, multiple-choice cloze and multiple-choice test, on the pre-intermediate and intermediate test takers’ reading comprehension performance. To this end, 40 pre-intermediate and intermediate learners par...

in this study, polystyrene ethylene butylene polystyrene (psebs) was functionalized to prepare mono and bipolar ion exchange membranes. in the case of the bipolar membrane, platinum was used as the intermediate layer. nacl solution of concentration ranging from 5 g/l to 25 g/l was used as the feed solution. a commercially procured ion exchange membrane made of polystyrene divinyl benzene was al...

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data envelopment analysis (dea) is a method for measuring the efficiency of peer decision making units (dmus) with multiple inputs and outputs. the traditional dea treats decision making units under evaluation as black boxes and calculates their efficiencies with first inputs and last outputs. this carries the notion of missing some intermediate measures in the process of changing the inputs to...