INTRODUCTION Complex retinal arterial macroaneurysms (RAM) are often accompanied by hemorrhage and/or affect the macula. We evaluated the effect of intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy using ranibizumab or aflibercept with or without laser photocoagulation in the treatment of macular edema due to RAM. METHODS A case report of two patients with secondary mac...

PURPOSE To estimate the 3-year incidence of exudative age-related macular degeneration (AMD) and its treatment by laser photocoagulation in elderly Americans. DESIGN Population-based cohort study using insurance claims data. PARTICIPANTS A random 5% sample of Medicare beneficiaries, age 65 and older. METHODS Incidence of exudative AMD and of laser photocoagulation for this condition was a...

PURPOSE To evaluate the effectiveness of laser photocoagulation as adjuvant therapy in the treatment of large macular holes. METHODS A randomized clinical trial. Thirty-one eyes from 29 subjects with idiopathic macular holes of diameters larger than 400 microm were randomized into a laser group and a control group. All eyes underwent vitrectomy with peeling of the internal limiting membrane. ...

Acute and chronic experiments were carried out in 26 beagle dogs to study the safety and efficacy of Neodymium-Yag laser photocoagulation in the treatment of bleeding gastric lesions. Continuous high power (50-60 W) Neodymium-Yag laser photocoagulation applied to the exposed stomach of the dog produced evaporation lesions that reached the muscle layer after six to 10 seconds and caused free per...

PURPOSE To evaluate the efficacy of vitrectomy combined with intravitreal injection of triamcinolone acetonide (IVTA) and macular laser photocoagulation for the treatment of nontractional diabetic macular edema (DME) refractory to anti-vascular endothelial growth factor (VEGF) therapy. METHODS Twenty-eight eyes from 28 subjects who were diagnosed with nontractional DME refractory to three or ...

OBJECTIVE To study the incidence and risk factors predisposing to retinopathy of prematurity (ROP) and to assess the outcome after laser photocoagulation. DESIGN Prospective cohort observational study. SETTING Infants admitted to a neonatal intensive care unit of a referral hospital between 2000-2006 and followed up till the age of 3 years. METHODS Preterm infants with birthweight<1500 g ...

PURPOSE The effectiveness and limitations of indocyanine green (ICG) enhanced diode laser photocoagulation in treating subfoveal choroidal neovascularization (CNV) associated with age-related macular degeneration (AMD) were investigated retrospectively. METHODS Thirty-eight eyes of 37 patients with subfoveal CNV received ICG enhanced diode laser (wavelength, 805 nm) photocoagulation in our pr...

BACKGROUND Idiopathic juxtafoveolar retinal telangiectasia (IJRT) type 1 represents an uncommon cause of congenital unilateral visual loss and it typically affects males. Decrease in visual acuity is caused by serous and lipid exudation into the fovea with cystoid macular edema. In some cases, spontaneous resolution may be observed, but when there is a progressive loss of visual acuity, laser p...

PURPOSE To evaluate the clinical features of Type 1 idiopathic macular telangiectasia (IMT) followed up for 2 years. METHODS Forty-nine patients with unilateral Type 1 IMT were examined. Thirty-one IMT eyes were treated with direct laser photocoagulation and/or intravitreal bevacizumab; the remaining 18 eyes, with good vision or slight macular edema, were untreated. Changes in best-corrected ...