BACKGROUND Rheumatoid arthritis (RA) commonly involves the knee joint in up to 30% of patients. Musculoskeletal ultrasound enables the skilled clinician to easily assess disease activity. OBJECTIVE To evaluate the sensitivity to change of the sonography score of large joints in Rheumatology (SOLAR) for different treatments of knee arthritis in RA. METHOD Joints were assessed by ultrasound a...

Background: In the treatment of moderate osteoarthritis with intraarticular injection there are many available options as steroid, hyaluronic acid and platelet rich plasma. But there are lack specific clear-cut indications. Our study is intended to compare result of different injections and correlate it to find some specific indication Method: Total 209 knees of 124 patients studied in three gr...

Invasive pulmonary aspergillosis (IPA) has emerged as a severe infection in patients with immunocompromised hosts. However, recently, several IPA cases, without an apparent predisposition to immunodeficiency, has been reported. A 72-year-old woman was admitted for evaluation of general weakness and poor oral intake. She reported no medical history, except for intraarticular injection of a corti...

OBJECTIVE To study the effect of intraarticular (IA) sympathetic blockade for the relief of resistant shoulder pain. METHODS Eighteen patients with shoulder pain resistant to conventional treatment were allocated randomly to two groups, to receive either IA guanethidine 20 mg or IA saline. They were assessed for pain, and range of active movements, before injection and at one, four, and eight...

OBJECTIVE To determine if colour Doppler ultrasonography can characterise the nature of intraarticular echogenic structures and synovial villi more precisely than conventional ultrasonography. METHODS This is a prospective study on 20 patients--10 with rheumatoid arthritis and 10 with osteoarthritis. Colour Doppler ultrasonography of the knee joints was performed prior to total prosthetic rep...

background: this double-blinded, randomized clinical trial was designed to evaluate the comparison of intravenous versus intraarticular (ia) administration of midazolam on postoperative pain after knee arthroscopy. materials and methods: in this study, 75 patients randomized in three groups to receive 75 mc/kg ia injection of midazolam and 10 ml intravenous injection of isotonic saline (group i...

INTRODUCTION It was previously shown that lipoxygenase (LO) pathways are important in the rheumatoid arthritis (RA) inflammatory process and that synovial fluid from RA patients contains high amounts of leukotrienes. We therefore aimed to investigate the 5-LO and 15-LO-1 expression pattern in RA and ostheoarthritis (OA) synovial tissue and to study the effect of intraarticular glucocorticoid (G...

INTRODUCTION Clinical and preclinical studies have shown that supplementation with ω-3 polyunsaturated fatty acids (ω-3 PUFAs) reduce joint destruction and inflammation present in rheumatoid arthritis (RA). However, the effects of individual ω-3 PUFAs on chronic arthritic pain have not been evaluated to date. Thus, our aim in this study was to examine whether purified docosahexaenoic acid (DHA,...