559 Introduction 559 Clinical Material 562 Site of Aneurysm, Interval From SAH to Randomization 563 Treatment Followed According to Protocol 564 Age and Neurological Condition Related to Mortality 565 Age and Medical Condition Related to Mortality 569 Mortality With Respect to Neurological Condition and Interval From Lait Bleed to Surgery 572 Rebleeding Prior to Surgery 575 Cerebral Angiography...

BACKGROUND AND PURPOSE Chronic inflammation is postulated as an important phenomenon in intracranial aneurysm wall pathophysiology. This study was conducted to determine if aspirin use impacts the occurrence of intracranial aneurysm rupture. METHODS Subjects enrolled in the International Study of Unruptured Intracranial Aneurysms (ISUIA) were selected from the prospective untreated cohort (n=...

Objective Intracranial vertebral artery dissecting aneurysms are rare lesions that are considered an important cause of spontaneous subarachnoid hemorrhage. We report our decade-long experience in treating ruptured intracranial vertebral artery dissecting aneurysms. Materials and Methods This retrospective single-center study included 21 consecutive patients between February 2005 and March 20...

Intracranial aneurysm (IA) accounts for 85% of Subarachnoid Hemorrhage (SAH) and is mainly caused due to the weakening of arterial wall. The structural integrity of the intracranial arteries is mainly influenced by the extracellular matrix (ECM) remodeling. The Proteoglycan Versican plays an important role in extracellular matrix assembly and plays a major role in the pathogenesis of IA. The li...

Intracranial aneurysms are localized, abnormal, arterial dilations with a variable risk of rupture, which can lead to subarachnoid hemorrhage (SAH), a condition associated with high morbidity and mortality. The majority of non-traumatic SAH cases are caused by ruptured intracranial aneurysms. Accurate detection can decrease a significant proportion of misdiagnosed cases. However, only a small p...

Background: The development of three-dimensional (3D) printing technology provides a new method for surgical treatment, but currently there are few reports on its application in the treatment of aneurysm. The aim of the present study was to explore the materials and methods of fabricating 3D printed individual aneurysm model and its value in the treatment of intracranial aneurysm. Methods: Twen...

BACKGROUND COL1A2, which encodes collagen type I alpha2, has long been suggested to be a potential positional and functional candidate gene for intracranial aneurysm. We performed a meta-analysis to assess the association between COL1A2 rs42524 polymorphism and the risk of intracranial aneurysm. MATERIAL AND METHODS We conducted a systematic search for relevant literature from the following dat...