INTRODUCTION Dexchlorpheniramine (DH) is a classical or first generation antihistamine belonging to the ethanolamine group. Adverse effects related to these antihistamines are frequent, but the hypersensitivity reactions described in the literature since 1940 are exceptional. We report the case of a 32-year-old woman who experienced two episodes of akathisia secondary to intravenous (i.v.) dexc...

background: considering the dramatic increasing rate of diabetes and consequently its related complications, most importantly diabetic peripheral neuropathy (dpn), challenges regarding proper treatment of dpn and its effect on the quality-of-life and care of diabetic patients, the aim of this current study is to evaluate the effect of intradermal botulinum toxin type a (btx-a) injections on pai...

BACKGROUND Frey s syndrome or Gustatory sweating was first described by Baillarger in 1853. Lucie Frey had described a patient as "auriculotemporal syndrome" in 1923. The explanation for this symptom has been an aberrant regeneration of postganglionic parasympathetic fibers feeding the parotid gland that are severed during parotidectomy. After parotidectomy, these cholinergic parasympathetic fi...

MycobacteriuM bovis is the bovine tuberculosis (bTB) agent, which is still an important infection in bovine herds. Apart from this, bTB is also a zoonotic disease, and human beings can be infected by the consumption of non-pasteurised milk and its derivatives (Michel and others 2010). Hence, bTB is still endemic worldwide (Humblet and others 2009). The single intradermal test (SIT) is a worldwi...

BACKGROUND Allergic rhinitis is the most common form of allergy worldwide. The accuracy of skin testing for allergic rhinitis is still debated. Our primary objective was to evaluate the diagnostic accuracy of skin-prick testing for allergic rhinitis using the nasal provocation as the reference standard. We also evaluated the diagnostic accuracy of intradermal testing as a secondary objective. ...

Insulin allergy has been uncommon since the introduction of human recombinant insulin preparations; the prevalence is 2.4%. Insulin injection could elicit immediate reactions, which are usually induced by an IgE-mediated mechanism, within the first hour after drug administration. In the present study, we describe the case of a child who experienced immediate urticaria after long-acting insulin ...

Intradermal melanoma on a pre-existing intradermal nevus is an exceptional finding. Since 1961, a total of 11 cases have been published; none of these were in the Spanish medical literature (PubMed, December 27, 2014). We report the case of a 42-year-old man who underwent treatment at his health center for a lesion in the center of his forehead. In the clinical history, the lesion was described...