OPINION STATEMENT Malignant peritoneal mesothelioma (MPM) is an aggressive neoplasm that rapidly spreads within the confines of the abdominal cavity to involve most accessible peritoneal and omental surfaces. Current treatment options are unsatisfactory, and new approaches are needed. Recent publications have reported improved survival with an intensive loco-regional treatment strategy includin...

Photorefractive keratectomy (PRK) remodels corneal stroma to compensate refractive errors. The removal of epithelium and the ablation of stroma provoke the disruption of corneal nerves and a release of several peptides from tears, epithelium, stroma and nerves. A myriad of cytokines, growth factors, and matrix metalloproteases participate in the process of corneal wound healing. Their balance w...

intraoperative radiation therapy (iort) is a multidisciplinary approach in which residual tumors or tumor beds are directly irradiated during a surgical procedure. to evaluate its efficacy, from 1985, we conducted a prospective study including non-metastatic gastric adenocarcinoma treated by surgery, iort (15 grays) and postoperative external beam radiotherapy (44 grays). up to 1993, 51 cases o...

OBJECTIVE To determine the re-recurrence and the postoperative complications in recurrent pterygium cases treated by intraoperative 0.02% Mitomycin C (MMC) and conjunctival autograft (CAG). STUDY DESIGN Quasi-experimental. PLACE AND DURATION OF STUDY Department of Ophthalmology, Liaquat University of Medical and Health Sciences, Jamshoro, Hyderabad and Chandka Medical College Hospital, Lark...

PURPOSE To study the effects of mitomycin-C (MMC) on the corneal endothelium after pterygium surgery. METHODS Prospective, interventional, nonrandomized, observer-masked study. Twenty patients (20 eyes) with primary pterygium underwent surgery with pterygium simple excision followed by 0.02% MMC application for 1 minute. Preoperative, 10-day, 1-month and 3-month postoperative specular microsc...

PURPOSE To evaluate the current clinical evidence of safety and efficacy of intraoperative topical application of 0.02% mitomycin C (MMC) used for up to 2 minutes after surface ablation for correction of myopia. METHODS A comprehensive literature search was conducted of Cochrane Library, MEDLINE, and EMBASE to identify relevant trials comparing surface ablation for correction of myopia with a...

.. Objective: To study the results of primary pterygium excision through bare sclera technique with and without intraoperative Mitomycin C use. Study design: This was an experimental study with randomised controlled trial. Setting and Duration: This study was conducted at Eye A unit, Khyber Teaching Hospital, Peshawar from May,2007 to April,2009. Methodology: One hundred patients with primary p...

AIM To find the risk factors related to the reproliferation of the pterygial tissue after excision and graft surgery. METHODS Charts of 130 eyes of 130 patients who had pterygial excision from March 2006 to April 2011 were reviewed. Preoperative pterygium morphology, surgical methods, and adjunctive treatments were statistically analyzed for their relationship with recurrence. RESULTS Durin...

PURPOSE To determine the occurrence of intraoperative and postoperative complications up to three years after primary phacotrabeculectomy with intraoperative use of Mitomycin C (MMC) in primary open angle (POAG) and primary angle closure glaucoma (PACG) patients, and the effect of postoperative complications on surgical outcome. METHODS Retrospective review of 160 consecutive patients with PO...