Objective to identify the impact of adhesions related to endometriosis on quality of life among infertile women. MaterialsAndMethods Cross-sectional, correlational study design was used. The study was performed at Endoscopic Unit, in Zagazig University Hospitals, Egypt. Oral consent to participate in this study was taken from 109 women who were candidates for laparoscopy as infertile cases and ...

Intrauterine adhesion (IUA) is a common cause for secondary infertility. However, traditional treatment nowadays can only restore the shape of the uterine cavity but not the inadequate endometrium. In this study, we investigated the therapeutic potentials of induced pluripotent stem cells (iPSCs) to treat IUA in a mouse model and further explore the role of heme-oxygenase-1 (HO-1) gene in exert...

time point. When comparing those who completed both baseline and Cycle1 GAD-7, a statistically significant increase in anxiety levels was observed in females (p1⁄40.02), but not in males. CONCLUSIONS: Although no significant change in depression was observed, we did note a statistically significant increase in mild anxiety in females upon initiating fertility treatment. The clinical significanc...

Objective: The aim of this study is to investigate the effects of human umbilical cord mesenchymal stem cells (hUCMSCs) transplantation on a rat model with intrauterine adhesions (IUA). Methods: 30 healthy female Sprague-Dawley rats were randomly divided into a sham operated group, a PBS group and a hUCMSCs group. The hUCMSCs were injected into uterines of the rat models in hUCMSCs group, and t...

Intrauterine adhesions (IUA) are a significant cause of menstrual disturbance and infertility, but their pathogenesis still remains unclear. Here, we investigated the expression of TGF-β and CCN2 in IUA endometrial tissue by immunohistochemistry, western blotting and qRT-PCR assays, and found the expression of TGF-β and CCN2 in the endometrial tissue of IUA was significantly increased compared ...

Intrauterine adhesions cause several gynecological problems. Althaea officinalis L. roots known as marshmallows contain polysaccharides (M.P.) which possess anti-inflammatory and anti-ulcerogenic activities also can form a bio-adhesive layer on damaged epithelial membranes prompting healing processes. Vaginal formulations of herbal origin are commonly applied to relieve cervico-uterine inflamma...