Roberts I, Yates D, Sandercock P, Farrell B, Wasserberg J, Lomas G, Cottingham R, Svoboda P, Brayley N, Mazairac G, Laloe V, Munoz-Sanchez A, Arango M, Hartzenberg B, Khamis H, Yutthakasemsunt S, Komolafe E, Olldashi F, Yadav Y, Murillo-Cabezas F, Shakur H, Edwards P: Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH...

Methods: Fifteen extended-spectrum b-lactamaseor carbapenemase-producing E. coli were studied. The in vitro pharmacodynamic model was inoculated with 1×10 cfu/mL and ertapenem was dosed once daily at 0 and 24 h to simulate free ( f ) Cmax and t12 obtained after either 1 g or 2 g intravenous once-daily doses in healthy volunteers (1 g: f Cmax 15 mg/L, t12 4 h). Sampling was performed over 48 h t...

Smoothed Particle Hydrodynamics (SPH) is a particle method to simulate compressible uids. First we present a brief introduction to SPH, where we focus on an approach to treat the physical viscosity. Then we describe in detail the basic principles of our parallel implementation of the SPH method. The eeciency of the code on Cray T3E and IBM SP2 is discussed. In the last part we present a short i...

The Internet of Things (IoT) Physical objects (or Groups such materials) sensors, processing Skills, software and the or other Communication connects with devices systems in exchange via networks Described as technologies. Invalid due to Devices Considered by name, they are associated public Internet. No need connect, just network Should only be connected can addressed individually. ability pro...

the technique of intraosseous (io) infusion has been reemerged as an alternative route of intravascular access for the delivery of fluids and some medications. complications of io infusion occur rarely and include fractures and osteomyelitis after long-term use of io access. the purpose of this study was to compare the efficiency of induction of anaesthesia by a standard intravenous route and a...

results the diagnostic value of ivu was found positive in 6.5% while it was negative in (93.5%) cases. the sensitivity and specificity of usg, rad and their combination in detection of urolithiasis was calculated as 90.5% and 84.8%, 84.1% and 88.6%; and 98.4% and 4.8% respectively. conclusions ivu can be largely replaced by usg in the pediatric population and if really clinically needed, its in...

UNLABELLED Quantitative small-animal PET of mice requires successful delivery of radiotracers into the venous system. Intravenous injection of radiotracers via lateral tail veins is the most commonly used method of administration and can be technically challenging. Evaluation of the quality of an intravenous injection is necessary to determine whether small-animal PET is quantitatively accurate...

BACKGROUND Pharmacokinetic estimates for intravenous paracetamol in individual adult cohorts are different to a certain extent, and understanding the covariates of these differences may guide dose individualization. In order to assess covariate effects of intravenous paracetamol disposition in adults, pharmacokinetic data on discrete studies were pooled. METHODS This pooled analysis was based...

Intra-amniotic injection of either prostaglandin F(2)alpha or prostaglandin E(2) was used in an attempt to induce therapeutic abortion in mid-pregnancy in 27 patients. Termination of pregnancy was successful in 11 out of 13 cases when prostaglandin E(2) alone was used, but in only 6 out of 14 cases when prostaglandin F(2)alpha was used. A further eight patients aborted after additional intraven...

Consider inviscid ‡uids in a channel f 1 < y < 1g. For the Couette ‡ow ~v0 = (y; 0), the vertical velocity of solutions to the linearized Euler equation at ~v0 decays in time. At the nonlinear level, such inviscid damping is widely open. First, we show that in any (vorticity) H s < 3 2 neighborhood of Couette ‡ow, there exist non-parallel steady ‡ows with arbitrary minimal horizontal period. Th...