BACKGROUND Although the anesthetic effects of the intravenous anesthetic agent propofol have been studied in the living human brain using brain imaging technology, the nature of the anesthetic state evident in the human brain during inhalational anesthesia remains unknown. To examine this issue, the authors studied the effects of isoflurane anesthesia on human cerebral glucose metabolism using ...

Based on theoretical grounds, remifentanil, an ultra-short acting opioid, has a favorable pharmacodynamic and pharmacokinetic profile for obstetric anesthesia/analgesia (13). When regional anesthesia is contraindicated, remifentanil is an intriguing option to provide labor analgesia using patient controlled intravenous analgesia (PCIA) (22). The rapid onset and offset would allow easy titration...

BACKGROUND Anesthesia and inflammatory response have been studied in major abdominal and thoracic surgical procedures, but not in major orthopaedic reconstructive procedures such as total knee arthroplasty. Most studies have compared general anesthesia with epidural anesthesia, but none has compared epidural with spinal. MATERIAL/METHODS In a prospective randomized study, 2 groups of patients...

In this review we addressed the various analgesic techniques in cardiac surgery, especially regional methods such as thoracic epidural anesthesia (TEA). There are many techniques available for management of postoperative pain after cardiac operation including intravenous administration of analgesic drugs, infiltration of local anesthetics, nerve blocks, and neuroaxial techniques. Although there...

BACKGROUND There is a continuing trend to have more elective surgery performed on an outpatient basis. OBJECTIVE To determine anesthetic profiles and adverse events in practice of ambulatory anesthesia for elective surgery in different levels of hospitals across Thailand. MATERIAL AND METHOD A prospective descriptive study was conducted in 20 hospitals comprising seven university, five regi...

Today many surgical procedures involving head and neck areas can be performed under local anesthesia and intravenous sedation. The authors add to this list the sagittal osteotomies of the mandibular rami, thereby avoiding the need for general anesthesia and a hospital stay. The authors designed a protocol to be followed in a multicenter study (Milan and Barcelona) and applied it in 35 clinical ...