Microemulsions improve the transdermal delivery of several drugs over conventional topical preparations such as emulsions and gels: enhanced drug solubilization, increased skin flux, decreased diffusion coefficient. Microemulsion-based systems find significant improvement in antifungals. We believe that drug-loaded microemulsion will show better antifungal activity by penetration into fungal ce...

This paper reports investigations into the preparation and characterization of surface molecularly imprinted nanoparticles (SMINs) designed to adhere to Helicobacter pylori (H. pylori). Imprinted nanoparticles were prepared by the inverse microemulsion polymerization method. A fraction of Lpp20, an outer membrane protein of H. pylori known as NQA, was chosen as template and modified with myrist...

We study the stationary and transient behaviors of a microemulsion phase subjected to a shear flow. The system is described by a diffusion-convective equation that generalizes the usual Cahn-Hilliard equation. Nonlinear terms are treated in a self-consistent approximation. Shear, first and second normal stresses are calculated as momenta of the structure factor. Shear thinning is observed in st...

Microemulsions are psuedohomogeneous mixtures which may show special performance towards reaction equilibria, nanoscale synthesis and reaction dynamics. Rate of reaction are most often accelerated in microemulsion media compared to that in water. This study is an effort to review some important reaction kinetics measured in reverse micro emulsion media. In the same time some pioneering research...

Microemulsion based cyclosporine has demonstrated better absorption with laser pharmacokinetic variability. For the clinical use of any new microemulsion based product, bioequivalence testing with existing formulation is necessary. Panimun Bioral (Test) and Sandimmun Neoral (Reference) were evaluated in different transplant centers using both volunteers as well as renal transplant patients. All...

The phase behavior for systems containing sodium bis(2-ethylhexyl sulfosuccinate) (AOT), with the cationic hydrotrope tetraethyl ammonium chloride (TEAC), in the presence of water and heptane were studied. Formulations of microemulsion for such systems and for systems containing the so called “extended surfactant” were carried out at different salt concentrations. Anisotropy was detected using ...

Mannosylerythritol lipid-A (MEL-A) is a glycolipid biosurfactant abundantly produced from soybean oil by microorganisms at a yield of up to 100 g/L. In this study, the formation of water-in-oil (W/O) microemulsion based on the single component of MEL-A was confirmed using dynamic light scattering (DLS) and freeze fracture electron microscopy (FF-EM). DLS and FF-EM measurements revealed that the...

Temperature dependent phase behavior of Pseudo-ternary Thiourea X-100 +1-hexanol (1:5 molar ratios)/oil/water systems is reported. The influence of nature of hydrocarbon oil and type of electrolytes (weak as well as strong) has been investigated on the temperature induced phase behavior of the ternary system. At surfactant concentration, Φs = 40%, a “nose shaped” microemulsion region is observe...

Ž . Ultrafine lead titanate PbTiO powders in tetragonal form have been successfully prepared via two processing routes, 3 Ž . Ž . namely, conventional coprecipitation CPC and microemulsion-refined coprecipitation MCP . The formation process of lead titanate from the resulting precursors was monitored using techniques such as thermal analyses, FTIR spectroscopy, Raman scattering spectroscopy and...

Microemulsions prepared by using either sodium dodecyl sulfate (SDS) or trimethyltetradecylammonium bromide (TTAB) were tested with regard to the migration time, selectivity and number of theoretical plates using a set of both water-soluble and lipid-soluble vitamins. While in the separations where SDS was used as the surface-active agent for microemulsion preparation, better resolutions were o...