The objective of this study has been to compare treatment plans for patients treated with electronic brachytherapy (eBx) using the Axxent System as adjuvant therapy for early stage breast cancer with treatment plans prepared from the same CT image sets using an Ir-192 source. Patients were implanted with an appropriately sized Axxent balloon applicator based on tumor cavity size and shape. A CT...

BACKGROUND Gel polymers are considered as new dosimeters for determining radiotherapy dose distribution in three dimensions. OBJECTIVE The ability of a new formulation of MAGIC-f polymer gel was assessed by experimental measurement and Monte Carlo (MC) method for studying the effect of gold nanoparticles (GNPs) in prostate dose distributions under the internal Ir-192 and external 18MV radioth...

BACKGROUND To examine the role of brachytherapy for aged patients 80 or more in the trend of rapidly increasing number. METHODS We examined the outcomes for elderly patients with node negative oral tongue cancer (T1-3N0M0) treated with brachytherapy. The 21 patients (2 T1, 14 T2, and 5 T3 cases) ranged in age from 80 to 89 years (median 81), and their cancer was pathologically confirmed. All ...

PURPOSE The dose delivered with a HDR (192)Ir afterloader can be separated into a dwell component, and a transit component resulting from the source movement. The transit component is directly dependent on the source speed profile and it is the goal of this study to measure accurate source speed profiles. METHODS A high speed video camera was used to record the movement of a (192)Ir source (N...

PURPOSE The aim of this study is to compare the dose in various soft tissues in brachytherapy with photon emitting sources. MATERIAL AND METHODS (103)Pd, (125)I, (169)Yb, (192)Ir brachytherapy sources were simulated with MCNPX Monte Carlo code, and their dose rate constant and radial dose function were compared with the published data. A spherical phantom with 50 cm radius was simulated and t...

Systemic and local inflammatory processes have a key, mainly detrimental role in the pathophysiology of ischemic stroke. Currently, little is known about endogenous counterregulatory immune mechanisms. We examined the role of the key immunomodulators CD4+CD25+ forkhead box P3 (Foxp3)+ regulatory T lymphocytes (Treg cells), after experimental brain ischemia. Depletion of Treg cells profoundly in...

1 Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Allerji ve İmmünoloji Bilim Dalı, Konya, 2 Gazi Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Ankara, 3 Adnan Menderes Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Aydın, 4 Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Pediatrik Göğüs Hastalıkları Bilim Dalı, Konya, 5 Cela...