molecular features of DS-ALL, is an avenue that may eventually enable safe reductions in conventional chemotherapy. As survival has improved in pediatric ALL, the need for efforts to reduce IRM is clear. This work by O’Connor and colleagues is a valuable contribution to the field, demonstrating the importance of capturing well-defined toxicity data on large cooperative group trials and identify...

OBJECTIVE To compare mean micro-leakage around 3 types of temporary restorative materials in-vitro, when placed adjacent to permanent restorations (amalgam) in complex endodontic access cavities. STUDY DESIGN Randomized controlled trial. PLACE AND DURATION OF STUDY Dental Clinics, Dental Laboratory and Research Laboratory at The Aga Khan University Hospital, Karachi, from January to June 20...

PURPOSE The aims of this study were to: (1) retrospectively assess the overall performance of formocresol pulpotomies in primary molars when definitively restored with a resin-based material; and (2) compare the results to previously published studies using more traditional restorative techniques (stainless steel crown, amalgam). METHODS Records of a 2-operator pediatric dental office using t...

Abstract The ionization region model (IRM) is applied to a high power impulse magnetron sputtering discharge with tungsten target. IRM gives the temporal variation of various species and average electron energy, as well internal parameters such probability back-attraction sputtered species. It shown that an initial peak in current due argon ions bombarding cathode After peak, W + become dominat...

BACKGROUND Intraoperative Radiotherapy (IORT) is a method by which a critical radiation dose is delivered to the tumour bed immediately after surgical excision. It is being investigated whether a single high dose of radiation will impart the same clinical benefit as a standard course of external beam therapy. Our centre has four Photon Radiosurgery Systems (PRS) currently used to irradiate brea...

The European Commission’s Seventh Framework Programme PRONTO project emphasizes the role of event recognition in intelligent resource management (IRM) and proposes a methodology for fusing data from various sources, analysing it to extract useful information—in the form of events— and delivering the resulting knowledge for decision making. To achieve this, PRONTO uses methods and expertise from...

Theoretically based behavioral interventions have demonstrated effectiveness in stopping smoking, increasing physical activity and improving nutrition in order to prevent major chronic diseases such as cardiovascular disease, cancer and diabetes [1–7]. Despite the development of effective behavior change programs, the magnitude of change in these behaviors has been relatively modest [8, 9]. The...