Intravenous iron therapy is a useful treatment for the rapid correction of iron deficiency anaemia and can be used to avoid or reduce the requirement for allogeneic blood transfusion. Several intravenous iron preparations are available commercially which differ in cost, mode of administration and side effect profile. There are few data directly comparing the efficacy of these preparations. In t...

Objectives: The aim of our study was to compare the effects of intravenous ferrous sucrose versus oral ferrous sulphate on postpartum iron deficiency anaemia. Material and methods: This prospective randomized study was conducted in Obstetrics and Gynaecology Department of Alkhidmat Teaching Hospital Mansoorah Lahore and in the Obstetrics and Gynaecology Department of Akhtar Saeed Trust Hospital...

Iron sucrose originator (IS(ORIG)) has been used to treat iron deficiency and iron deficiency anemia for decades. Iron sucrose similars (ISSs) have recently entered the market. In this non-clinical study of non-anemic rats, five doses (40 mg iron/kg body weight) of six ISSs marketed in Asian countries, IS(ORIG) or saline solution (control) were administered intravenously over four weeks to comp...

Iron deficiency anaemia is one of the most common disorders in the world. Also, one third of inflammatory bowel disease (IBD) patients suffer from recurrent anaemia. Anaemia has significant impact on the quality of life of affected patients. Chronic fatigue, a frequent IBD symptom itself, is commonly caused by anaemia and may debilitate patients as much as abdominal pain or diarrhoea. Common th...

The title compound, Nd(3)Fe(5)O(12) (NdIG), has an iron garnet structure. One of the Fe atoms is coordinated by six O atoms in a slightly distorted octa-hedral geometry and has site symmetry. The other Fe atom is coordinated by four O atoms in a slightly distorted tetra-hedral geometry and has site symmetry. The FeO(6) octa-hedron and FeO(4) tetra-hedron are linked together by corners. The Nd a...

Serious concerns have been raised with respect to intravenous (i.v.) iron as a potential oxidative stress inducer in chronic kidney disease patients. Oxidative stress has been linked to uremia-related inflammation and endothelial dysfunction. Because i.v. iron promotes oxidative stress and because uremic patients have numerous defects of antioxidant defense unrelated to iron, we hypothesized th...