Purpose: The purpose of this work is to study and quantify the differences in calculated dose computed with two algorithms available in treatment planning systems: Pencil Beam Convolution and Clarkson. Material and Methods: Four different types of treatment cases were analyzed: lung, head and neck, brain and prostate. For each case, the volume definition was based on a clinical CT-scan acquisit...

AIM The purpose of this study is to calculate radiation dose around a brachytherapy source in a water phantom for different seed locations or rotation the sources by the matrix summation method. BACKGROUND Monte Carlo based codes like MCNP are widely used for performing radiation transport calculations and dose evaluation in brachytherapy. But for complicated situations, like using more than ...

PURPOSE A "dose bricks" concept has been used to implement nasopharyngeal carcinoma treatment plan; this method specializes particularly in the case with bell shape nasopharyngeal carcinoma case. MATERIALS AND METHODS Five noncoplanar fields were used to accomplish the dose bricks technique treatment plan. These five fields include (a) right superior anterior oblique (RSAO), (b) left superior...

A general-purpose, object oriented software system has been developed for the simulation and dosimetric analysis of brachytherapy applications. The flexible object-oriented design makes this system very versatile, offering the possibility to configure it for different types of brachytherapy techniques (such as I-125 or Ir-192, for instance). The dosimetric system is based on the Geant4 Simulati...

PURPOSE In this work, gold nanoparticles (GNPs) were embedded in the MAGIC-f polymer gel irradiated with the 192Ir brachytherapy sources. MATERIAL AND METHODS At the first plexiglas phantom was made as the human pelvis. The GNPs were synthesized with 15 nm in diameter and 0.1 mM (0.0197 mg/ml) in concentration by using a chemical reduction method. Then, the MAGIC-f gel was synthesized. The fa...

BACKGROUND AND OBJECTIVES Irradiation of whole blood and blood components before transfusion is currently the only accepted methodology to prevent transfusion-associated graft-vs.-host disease. In the present work, we developed an automated system for blood bag storage during irradiation, using a teletherapy unit. MATERIALS AND METHODS A device with two thermal compartments was constructed in...

OBJECTIVE The behavior of beta particles under the magnetic field was investigated both theoretically and experimentally based on the assumption of reducing the damage to the normal tissues created by using magnetic field in radionuclide therapy. METHODS A water-filled spherical medium and a beta particle source was formed by using Geant4 simulation software for the theoretical study. After a...

BACKGROUND AND PURPOSE This study compares dosimetric parameters of planning target volume (PTV) coverage and organs at risk (OAR) sparing when postoperative radiotherapy for gynecologic cancers is delivered using volumetric modulated arc therapy (VMAT) versus a four-field (4FLD) box technique. MATERIAL AND METHODS From July to December 2012, women requiring postoperative radiation for gyneco...

Intraoperative radiotherapy (IORT) is a relatively new technique in which irradiation with electrons is performed during an open surgery procedure. This approach poses significant problems in obtaining accurate dosimetry, since neither the pre- nor the postoperative patient images actually matches the irradiation field. Our objective was to implement a software tool able to provide an estimate ...