Nakamura, Tomoe Y., William A. Coetzee, Eleazar Vega-Saenz De Miera, Michael Artman, and Bernardo Rudy. Modulation of Kv4 channels, key components of rat ventricular transient outward K1 current, by PKC. Am. J. Physiol. 273 (Heart Circ. Physiol. 42): H1775–H1786, 1997.— Current evidence suggests that members of the Kv4 subfamily may encode native cardiac transient outward current (Ito). Antisen...

OBJECTIVES Carcinogenicity and chronic toxicity of indium-tin oxide (ITO) were examined by inhalation exposure of rats and mice to ITO aerosol. METHODS Fifty mice of both sexes were exposed to ITO at 0 (control), 0.01, 0.03 or 0.1 mg/m(3) for 6 h/day, 5 day/wk for 104 wk, and 50 rats of both sexes were exposed to 0, 0.01 or 0.03 mg/m(3) ITO for the same time period. The repeated exposure of 5...

Hulme, J. T., and C. H. Orchard Effect of acidosis on transient outward potassium current in isolated rat ventricular myocytes. Am. J. Physiol. Heart Circ. Physiol. 278: H50–H59, 2000.—The effect of acidosis on the transient outward K1 current (Ito) of rat ventricular myocytes has been investigated using the perforated patch-clamp technique. When the holding potential was 280 mV, depolarizing p...

The object of this paper is to establish certain generalized fractional integration and differentiation involving generalized Mittag-Leffler function defined by Salim and Faraj [25]. The considered generalized fractional calculus operators contain the Appell's function $F_3$ [2, p.224] as kernel and are introduced by Saigo and Maeda [23]. The Marichev-Saigo-Maeda fractional calculus operators a...

Diffusion of silver(Ag) from the electrode in perovskite solar cell layers presence moisture is a serious issue fabrication stable halide perovskite-based cells (PSC). We witnessed fast degradation fabricated planar p-i-n PSC having device structure as glass/ITO/PEDOT:PSS/MAPbI3/PCBM/Ag. This due to ambient and reaction Ag with form silver iodide(AgI). The diffusion into was easily noticeable a...

In various mammalian species, shapes of action potentials vary within the cardiac wall because of differences in transient outward current (Ito). A prominent Ito exists in human ventricular myocytes, but cells have not been separated according to their original localization. Human ventricular myocytes were isolated from separated subepicardial and subendocardial tissue, and regional variations ...

This investigation reports on the characteristics of MAPbI3 perovskite films on obliquely sputtered ITO/glass substrates that are fabricated with various sputtering times and sputtering angles. The grain size of a MAPbI3 perovskite film increases with the oblique sputtering angle of ITO thin films from 0° to 80°, indicating that the surface properties of the ITO affect the wettability of the PE...

Given the immense variety of compounds being developed for introduction into the human environment, reliable medium term alternatives to traditional long term rodent test protocols for carcinogen risk assessment are a high priority. In vivo models are necessary because it has been well established that there is a lack of complete correlation between mutagenicity and carcinogenicity . Optimally,...