نتایج جستجو برای: jc virus
تعداد نتایج: 400574 فیلتر نتایج به سال:
Progressive multifocal leukoencephalopathy (PML) is a progressive demyelinating disease caused by JC virus, occurring in immunocompromised patients. In the HAART era, approximately 5% of the AIDS patients have been reported to develop PML. The clinical presentation of PML is quite variable because lesions may occur anywhere in the CNS white mater; the most common fi ndings are motor weakness, v...
The increased use of newer potent immunomodulatory therapies for multiple sclerosis (MS), including natalizumab, fingolimod, and dimethyl fumarate, has expanded the patient population at risk for developing progressive multifocal leukoencephalopathy (PML). These MS therapies shift the profile of lymphocytes within the central nervous system (CNS) leading to increased anti-inflammatory subsets a...
598.O’Brien P, Fleming T (1979). A multiple testing procedure for clinical trials. Biometrics 35: 549–556.Silver SA, Arthur RR, Erozan YS, Sherman ME, McArthur JC, Uematsu S (1995). Diagnosis of progressive multi-focal leukoencephalopathy by stereotactic brain biopsy utilizing immunohistochemistry and the polymerasechain reaction. Acta Cytol 39: 35–44. Sindic C, TrebstC, VanAntw...
Deep nucleotide sequencing enables the unbiased, broad-spectrum detection of viruses in clinical samples without requiring an a priori hypothesis for the source of infection. However, its use in clinical research applications is limited by low cost-effectiveness given that most of the sequencing information from clinical samples is related to the human genome, which renders the analysis of vira...
The purpose of this study is to disambiguate Japanese compound verbs (JCVs) using two methods: (1) a statistical sense discrimination method based on verbcombinatoric information, which feeds into a first-sense statistical sense disambiguation method, and (2) a manual rule-based sense disambiguation method which draws on argument structure and verb semantics. In evaluation, we found that the ru...
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