نتایج جستجو برای: kernicterus manifestation
تعداد نتایج: 33959 فیلتر نتایج به سال:
Children constitute a vulnerable group since a new drug gets released to the market without the benefit of even limited experience in them. Adequate controlled clinical trials in children, with the notable exceptions of pediatric oncology and vaccinations, are lacking because of ethical considerations. Only a vigilant postmarketing surveillance detects ADRs occurring uniquely in children, for e...
Protein phosphorylation in cerebral cell-free preparations from neonate rabbits was inhibited by bilirubin and promoted by aminophylline when these substances had been administered intravenously. In animals given both compounds, the bilirubin-induced inhibition of phosphorylation was partly reversed by aminophylline. Adenosine 3',5'-monophosphate added in vitro during the assays also increased ...
Abstract Background The risk of kernicterus and BIND may be in part determined by total serum bilirubin (TSB) the level non-albumin bound free bilirubin, which can easily pass blood–brain barrier. Free (Bf) seems a more reliable predictor for neurotoxicity. Bilirubin/albumin ratio (B/A) is considered surrogate parameter Bf has been useful than TSB. aim study to determine whether B/A correlates ...
OBJECTIVE The objective of this study was to determine whether transcutaneous bilirubin (TcB) measurements correlate with serum total bilirubin (STB) levels in indigenous, darkly pigmented African newborns with varying degrees of skin pigmentation, some of which had developed kernicterus. METHODS Jaundiced infants who were < or =2 weeks of age and admitted to Baptist Medical Center-Eku (Eku; ...
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