We studied 90 adults undergoing surgical removal of at least both lower third molar teeth as day cases under standardized general anaesthesia. Patients were allocated randomly (with stratification for surgeon) to receive tenoxicam 40 mg, tenoxicam 20 mg or placebo i.v. at induction of anaesthesia and orally (effervescent tablets) with food on each of the subsequent 2 days. Panadeine (paracetamo...

Abbreviations: ALT, alanine aminotransferase; APAP, acetaminophen; CoQ10, oxidized coenzyme Q10; CoQ9H2, reduced coenzyme Q9; CoQ10H2, reduced coenzyme Q10; CYP, cytochrome P450; GSH, reduced glutathione; GSSG, oxidized glutathione; HSP, heat shock protein; MEOS, microsomal ethanol oxidizing system; NAC, N-acetylcysteine; NAPQI, N-acetyl-p-benzoquinoneimine; ROS, reactive oxygen species; SAMC, ...

This research is aimed at producing alternative starch used for tablet binding from amura tuber. The microbiological load and physicochemical properties of native modified starches were determined using plate counting method standard BP. Amylose amylopectin content spectrophotometric method. Binding disintegrant abilities these studied paracetamol as a model drug. Paracetamol tablets formulated...

In this article, a combined method of molecular absorption spectroscopy and classical least squares is used to simultaneously determine paracetamol (PAR) codeine phosphate (COP) in pharmaceutical samples without the need for prior separation or extraction steps. The spectra standard solutions were measured wavelength range 210 290 nm with step size 0.5 nm. concentrations PAR COP sample calculat...

Text mining (TM) applications in the field of biomedicine are gaining great interest. TM tools can facilitate formulation development by analyzing textual information from patent databases, scientific articles, summary products characteristics, etc. The aim this study was to utilize perform qualitative analysis paracetamol (PAR) and ibuprofen (IBU) formulations, terms identifying evaluating pre...