نتایج جستجو برای: killer cells
تعداد نتایج: 1392378 فیلتر نتایج به سال:
We recently dissected how senescent tumors can trigger complementing signaling pathways that mobilize natural killer (NK) cells to eliminate malignant cells. In addition to cell-intrinsic effects on proliferation, senescence induces the production of chemokine (C-C motif) ligand 2 (CCL2), which recruits NK cells to mediate direct tumoricidal effects. Hence, senescence activates a cancer cell-ex...
GATA2 deficiency-formerly described as MonoMAC syndrome; dendritic cells, monocytes, B cells, and natural killer cell deficiency; familial myelodysplastic syndrome/acute myeloid leukemia; or Emberger syndrome-encompasses a range of hematologic and nonhematologic anomalies, mainly characterized by monocytopenia, B lymphopenia, natural killer cell cytopenia, neutropenia, immunodeficiency, and a h...
Two cases of obstinate cancers are cured by a new hypothesis synergistic therapy approach where Cancer Homoeotherapeutics were analysed scientifically immunotherapy modus operandi homoeopathic medicine selection is done activating natural cancer immunity killer cells (NK) through the interferon produced viral infection. So synthesis antiviral and antimiasmatic to treat cases.
Natural killer cells gauge the absence of self class I MHC on susceptible target cells by means of inhibitory receptors such as members of the Ly49 family. To initiate killing by natural killer cells, a lack of inhibitory signals must be accompanied by the presence of activating ligands on the target cell. Although natural killer cell-mediated rejection of class I MHC-deficient bone marrow (BM)...
Chinese hamster ovary cell lines with specific lesions in the formation of glycoconjugates were tested for their sensitivity to lysis by interferon-boosted human natural killer cells. We report here that the type of asparagine-linked carbohydrate present on target cell glycoproteins determines their susceptibility to natural killer lysis. The targets tested were Chinese hamster ovary parent cel...
background: the major immuno-modulating effects of ganoderma lucidum include mitogenicity and activation of immune effector cells such as t cells, macrophages and natural killer cells resulting in the production of cytokines. objective: the purpose of this study was to evaluate the expression of cd40 and cd80 by g. lucidum-treated human peripheral blood mononuclear cells. methods: monocytes wer...
Although various elements of the immune system are involved in detection and elimination of neoplastic cells, immune surveillance mechanisms are not always successful in eradicating cancer. Invariant natural killer T cells are potent immunomodulatory lymphocytes that secrete large amounts of Th-1 and/or Th-2 cytokines in response to glycolipid agonists. The observed role of invariant natural ki...
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