STOCK DEFINITION AND GEOGRAPHIC RANGE False killer whales are found worldwide mainly in tropical and warm-temperate waters (Stacey et al. 1994). In the North Pacific, this species is well known from southern Japan, Hawaii, and the eastern tropical Pacific. There are seven stranding records from Hawaiian waters since 1974 (Nitta 1991; Maldini et al. 2005, NMFS PIR Marine Mammal Response Network ...

STOCK DEFINITION AND GEOGRAPHIC RANGE False killer whales are found worldwide mainly in tropical and warmtemperate waters (Stacey et al. 1994). In the North Pacific, this species is well known from southern Japan, Hawaii, and the eastern tropical Pacific. There are six stranding records from Hawaiian waters (Nitta 1991; Maldini et al. 2005). One on-effort sighting of false killer whales was mad...

A halotolerant yeast, Pichia farinosa KK1 strain, produces a unique killer toxin termed SMK toxin (salt-mediated killer toxin) which shows its maximum killer activity in the presence of 2 M NaCl. The toxin consists of two distinct subunits, alpha and beta, which are tightly linked without a disulfide bond under acidic conditions, even in the presence of 6 M urea. Under neutral conditions, howev...

Linear DNA plasmids were found in the following yeasts: four strains of Kluyveromyces lactis, one of Debaryomyces hansenii, one of Wingea robertsiae and four of Pichia etchellsii. In each case, the plasmids were present as a pair of DNA molecules of different sizes. The plasmids of K. lactis strains were associated with a killer activity and their structure was similar to the known killer plasm...

CD96 is a membrane-bound receptor discovered in humans 1992 that mainly present natural killer cells and T derived from haematopoietic performs immune functions. Based on the sequence of obtained red seabream (Pagrus major), phylogenetic analysis with other species, infections normal fish, Streptococcus iniae sea bream iridovirus (RSIV), expression was conducted using real-time polymerase chain...

Objectives: Perforin and granzyme B are essential proteins for protective immune responses mediated by Cytotoxic T Lymphocytes (CTLs) Natural Killer cells (NK) against cancers, especially those of hematological origin. Our study investigated polymorphisms in the perforin gene (PRF1) quantified levels patients with multiple myeloma (MM). Methods: The PRF1 coding region was evaluated 58 MM 78 hea...

Gene-engineered immune cell therapies have partially transformed cancer treatment, as exemplified by the use of chimeric antigen receptor (CAR)-T cells in certain hematologic malignancies. However, there are several limitations that need to be addressed target more types. Natural killer (NK) a type innate represent unique biology surveillance. In particular, NK obtained from heathy donors can s...

Chronic myeloid leukemia (CML) is caused by the reciprocal translocation t(9;22)(q34;q11), resulting in BCR-ABL1 fusion gene. tyrosine kinase inhibitors (TKIs) improve overall survival patients with chronic phase CML (CML-CP). Approximately half of who achieve a durable deep molecular response can sustained treatment-free remission (TFR) after TKI discontinuation; thus TFR now therapeutic goal ...

background: schizophrenia has been associated with altered immunity. different studies regarding natural killer cell activity (nka) in schizophrenic patients have shown inconsistent results. objectives: to evaluate nk cell activity in schizophrenic patients in comparison with healthy control individuals.   methods: 30 medication-free schizophrenic patients and 41 healthy sex, age and smoking st...