Hepatoid carcinomas are a group of neoplasms with features resembling hepatocellular carcinomas. Although extremely rare, more cases have been noted to arise from various organs within the last decade. Differentiating these tumors when located in the biliary tree from cholangiocarcinoma is not only a radiologic challenge but also critical, because treatment modalities and operative strategies a...

Background: Hilar resection in combination with extended liver resections has resulted in a higher rate of R0 resections and increased survival in patients with hilar cholangiocarcinoma (HCCA). This aggressive surgical approach is, however, associated with high rates of operative morbidity and mortality, largely due to postresectional liver failure. We previously reported a series after resecti...

BACKGROUND AND STUDY AIMS Neoadjuvant chemotherapy (NAC) may lead to a successful margin-negative resection in patients with initially unresectable locally advanced Klatskin tumor (IULAKT). Use of removable plastic stents is preferable for the safe implementation of NAC in patients with IULAKT to reduce the risk of recurrent cholangitis. Our aim was to evaluate the efficacy associated with the ...

IgG4-related disease represents a heterogeneous group of disease characterized by infiltration of various tissues by IgG4 plasmocytes. In case of liver infiltration, this condition classically mimics primary sclerosing cholangitis or multifocal cholangiocarcinoma due to inflammation that preferentially affects the intra- and extrahepatic bile duct. Diagnostic criteria have recently been reviewe...

The patient was continued on ATRIPLA and finished 5 out of 6 cycles of R-CHOP-21 chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone), complicated by multiple episodes of neutropenic fever. After the 3rd cycle, a positron emission tomography/CT scan showed no evidence of active mass lesion or lymphadenopathy. After 10 months of follow-up, the patient continues to dem...

Cholangiocarcinoma is the 2nd most common primary hepatic malignancy with an incidence in the United States ranging from 0.40.9/100,000 with 5 year survival estimated at 2.6-4.4% [1]. The average age at diagnosis of cholangiocarcinoma is 50 years old with curative options including surgical resection, neoadjuvant chemoradiation, and liver transplantation [2]. Staging is based on anatomic locati...