HIGH RISK GENOTYPES AMONG IRANIAN HEALTHY WOMEN: A SYSTEMATIC REVIEW AND META-ANALYSIS Mina Malary, Mahmood Moosazadeh, Zeinab Hamzehgardeshi, Mahdi Afshari, Iman Moghaddasifar, Amin Afsharimoghadam. Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran; Assistant Professor, Health Sciences Research Center, Faculty of Health, Mazandaran University of Medical Sciences...

Since 1980, when the idea of drug-delivery was proposed, various drug-carriers have been developed, including DNA, proteins, liposomes and several other polymer cages, consisting of many well established natural and synthetic nano-particles. All these drug-carriers can self-assemble in the body and can be manipulated for safer delivery into target tissues. By definition, nano-scale drug deliver...

An experiment was conducted to examine effects of bovine ST (bST) on serum hormone concentrations, pregnancy rates, and offspring performance. Before initiation of a fall breeding period, 75 Rambouillet ewes (68.8 ± 1.5 kg) received an intravaginal insert containing 0.3 g of progesterone (P4) to synchronize onset of estrus. After 12 d, inserts were removed (d 0), and ewes (stratifi ed by BW and...

Two experiments were performed to determine the endocrine and ovarian changes in medroxyprogesterone acetate (MAP)-primed ewes after ram introduction. Experiment 1 was performed during the mid-breeding season with 71 ewes primed with an intravaginal MAP sponge for 12 days. While the control (C) ewes (n = 35) were in permanent contact with rams, the ram effect (RE) ewes (n = 36) were isolated fo...

Primiparous ewes born as singletons to Rambouillet x Columbia crossbred ewes fed either 100% of NRC recommendations (control, Con; n = 7) or 50% of NRC (nutrient restricted, NR; n = 7) from d 28 through 78 postmating were utilized for this study. At 1 yr of age, a subset of ewes born to Con (n = 4) and NR (n = 4) mothers received jugular catheters and were subjected to a corticotrophin-releasin...

Maternal renal disease is associated with high maternal and fetal morbidity. To establish an animal model to study renal dysfunction in pregnancy and its potential role in programming for renal disease and hypertension in adult life, a kidney was removed from each of 16 nonpregnant ewes, and a branch of the renal artery of the remaining kidney was ligated (STNx ewes). The 16 STNx and 15 intact ...

Twenty-four Comisana ewes, with no history of mastitis, were included in this study, with eight ewes each in parities 1, 2 and 3. Groups were separately penned on straw litter and ewes were individually checked for yield, composition, renneting properties and bacteriological characteristics of milk from January, when separated from their lambs (50+/-3 days after lambing), to May. Samples with m...

The objective was to determine the effect of dietary intake on follicle and oocyte morphology in unstimulated and superovulated ewes. Fifty-four ewes were fed grass meal at 0.5, 1.0 or 2.0 times maintenance energy requirements (M) for 32 days. Oestrous cycles were synchronized using progestagen pessaries and either unstimulated or superovulated with 200 mg pig FSH. The ewes were killed and ovar...

thin ewes or very over-conditioned ewes and ewes carrying multiple pregnanciesare more likely to develop pregnancy toxemia (ketosis). pregnancy toxemia is a metabolic disorder characterized by hypoglycemia and hyperketonemia resulting from incapacity of the ewes to maintain adequate energy balance (usually in the last 5-6 weeks).available information about pregnancy toxemia focuses mainly on pa...

Data of 23 189 Merino ewes (8 farms), 7692 Dohne Merino ewes (3 farms) and 2399 SA Mutton Merino ewes (1 farm) were recorded for the 1988-1991 lambing seasons. The udders of ewes present at lamb marking were inspected to differentiate between barren (unlambed), lambed and lost (lambed ewes suckling no progeny), and wet (lambed and suckling ~ 1 lamb) ewes, using the 'wet and dry' technique. The ...