Native-like production of intonational prominence is important for spoken language competency. Non-native speakers may have trouble producing prosodic variation in a second language (L2) and thus, problems in being understood. By identifying common sources of production error, we will be able to aid in the instruction of L2 speakers. In this paper we present results of a production study design...

Background: The P600 brain wave reflects syntactic processes in response to different first language (L1) syntactic violations, syntactic repair, structural reanalysis, and specific semantic components. Unlike semantic processing, aspects of the second language (L2) syntactic processing differ from the L1, particularly at lower levels of proficiency. At higher L2 proficiency, syntactic violatio...

in this paper, we nd the relationships between module contractibility of abanach algebra and its ideals. we also prove that module contractibility ofa banach algebra is equivalent to module contractibility of its module uniti-zation. finally, we show that when a maximal group homomorphic image ofan inverse semigroup s with the set of idempotents e is nite, the moduleprojective tensor product ...

Success of adoptive cell therapy mainly depends on the ability immune cells to persist and function optimally in immunosuppressive tumor microenvironment. Although present at cancer site, become exhausted and/or inhibited, due presence inhibitory receptors such as PD-L1 malignant cells. Novel genetic strategies manipulate PD1/PD-L1 axis comprise (i) PD-1 reversion where receptor intracellular d...

Human papillomavirus (HPV) major capsid protein L1 is an important vehicle for the delivery of epitopes. To investigate the expression and immunogenicity of hybridized HPV6b L1 containing multiepitope of Epstein-Barr virus (EBV) latency membrane protein 2 (LMP2), a recombinant plasmid pcDNA3.1(+) containing mammalian codon-optimization HPV6b L1 gene and EBV LMP2 multiepitope was constructed. Th...

The programmed cell death-1(PD-1)/PD-ligand 1 (PD-L1) pathway is critical to immune homeostasis by promoting regulatory T (Treg) development and inhibiting effector T (such as Th17) cell responses. However, the association between the PD-1/PD-L1 pathway and the Treg/Th17 imbalance has not been fully investigated in pre-eclampsia (PE). In this study, we observed an inverse correlation between th...

According  to  a  basic  prediction  made  by  the  Revised  Hierarchical  Model  (RHM),  at  early  stages  of language  acquisition,  strong  L2-L1  lexical  links  are  formed.  RHM  predicts  that  these  links  weaken with  increasing  proficiency,  although  they  do  not  disappear  even  at  higher  levels  of  language development. To test this prediction, two groups of highly proficie...